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This lesson is a general overview of overarching concepts in neuroinformatics research, with a particular focus on clinical approaches to defining, measuring, studying, diagnosing, and treating various brain disorders. Also described are the complex, multi-level nature of brain disorders and the data associated with them, from genes and individual cells up to cortical microcircuits and whole-brain network dynamics. Given the heterogeneity of brain disorders and their underlying mechanisms, this lesson lays out a case for multiscale neuroscience data integration.

Difficulty level: Intermediate
Duration: 1:09:33
Speaker: : Sean Hill

This lesson breaks down the principles of Bayesian inference and how it relates to cognitive processes and functions like learning and perception. It is then explained how cognitive models can be built using Bayesian statistics in order to investigate how our brains interface with their environment. 

This lesson corresponds to slides 1-64 in the PDF below. 

Difficulty level: Intermediate
Duration: 1:28:14

Whereas the previous two lessons described the biophysical and signalling properties of individual neurons, this lesson describes properties of those units when part of larger networks. 

Difficulty level: Intermediate
Duration: 6:00
Speaker: : Marcus Ghosh

This lesson goes over some examples of how machine learners and computational neuroscientists go about designing and building neural network models inspired by biological brain systems. 

Difficulty level: Intermediate
Duration: 12:52
Speaker: : Dan Goodman

This lecture presents an overview of functional brain parcellations, as well as a set of tutorials on bootstrap agregation of stable clusters (BASC) for fMRI brain parcellation.

Difficulty level: Advanced
Duration: 50:28
Speaker: : Pierre Bellec

This lecture covers a lot of post-war developments in the science of the mind, focusing first on the cognitive revolution, and concluding with living machines.

Difficulty level: Beginner
Duration: 2:24:35

This lecture provides an overview of depression (epidemiology and course of the disorder), clinical presentation, somatic co-morbidity, and treatment options.

Difficulty level: Beginner
Duration: 37:51

The state of the field regarding the diagnosis and treatment of major depressive disorder (MDD) is discussed. Current challenges and opportunities facing the research and clinical communities are outlined, including appropriate quantitative and qualitative analyses of the heterogeneity of biological, social, and psychiatric factors which may contribute to MDD.

Difficulty level: Beginner
Duration: 1:29:28

This lesson delves into the opportunities and challenges of telepsychiatry. While novel digital approaches to clinical research and care have the potential to improve and accelerate patient outcomes, researchers and care providers must consider new population factors, such as digital disparity. 

Difficulty level: Beginner
Duration: 1:20:28
Speaker: : Abhi Pratap

This lesson provides a basic introduction to clinical presentation of schizophrenia, its etiology, and current treatment options.

Difficulty level: Beginner
Duration: 51:49

While the previous lesson in the Neuro4ML course dealt with the mechanisms involved in individual synapses, this lesson discusses how synapses and their neurons' firing patterns may change over time. 

Difficulty level: Intermediate
Duration: 4:48
Speaker: : Marcus Ghosh

In this lesson, you will learn about the current challenges facing the integration of machine learning and neuroscience. 

Difficulty level: Beginner
Duration: 5:42
Speaker: : Dan Goodman

This lesson provides a brief overview of the Python programming language, with an emphasis on tools relevant to data scientists.

Difficulty level: Beginner
Duration: 1:16:36
Speaker: : Tal Yarkoni

This tutorial covers the fundamentals of collaborating with Git and GitHub.

Difficulty level: Intermediate
Duration: 2:15:50
Speaker: : Elizabeth DuPre

The lecture provides an overview of the core skills and practical solutions required to practice reproducible research.

Difficulty level: Beginner
Duration: 1:25:17
Speaker: : Fernando Perez

This lecture covers the description and brief history of data science and its use in neuroinformatics.

Difficulty level: Beginner
Duration: 11:15
Speaker: : Ariel Rokem

This lesson provides an overview of self-supervision as it relates to neural data tasks and the Mine Your Own vieW (MYOW) approach.

Difficulty level: Beginner
Duration: 25:50
Speaker: : Eva Dyer