Tutorial on how to perform multi-scale simulation of Alzheimer's disease on The Virtual Brain Simulation Platform. Authors: L. Stefanovski, P. Triebkorn, M.A. Diaz-Cortes, A. Solodkin, V. Jirsa, A.R. McIntosh, P. Ritter
Tutorial on how to simulate brain tumor brains with TVB (reproducing publication: Marinazzo et al. 2020 Neuroimage). This tutorial comprises a didactic video, jupyter notebooks, and full data set for the construction of virtual brains from patients and health controls. Authors: Hannelore Aerts, Michael Schirner, Ben Jeurissen, DIrk Van Roost, Eric Achten, Petra Ritter, Daniele Marinazzo
The tutorial comprises a didactic video and jupyter notebooks (reproducing publication: Falcon et al. 2016 eNeuro). Contributors: Daniele Marinazzo, Petra Ritter, Paul Triebkorn, Ana Solodkin
A brief overview of the Python programming language, with an emphasis on tools relevant to data scientists. This lecture was part of the 2018 Neurohackademy, a 2-week hands-on summer institute in neuroimaging and data science held at the University of Washington eScience Institute.
An introduction to data management, manipulation, visualization, and analysis for neuroscience. Students will learn scientific programming in Python, and use this to work with example data from areas such as cognitive-behavioral research, single-cell recording, EEG, and structural and functional MRI. Basic signal processing techniques including filtering are covered. The course includes a Jupyter Notebook and video tutorials.
The goal of computational modeling in behavioral and psychological science is using mathematical models to characterize behavioral (or neural) data. Over the past decade, this practice has revolutionized social psychological science (and neuroscience) by allowing researchers to formalize theories as constrained mathematical models and test specific hypotheses to explain unobservable aspects of complex social cognitive processes and behaviors. This course is composed of 4 modules in the format of Jupyter Notebooks. This course comprises lecture-based, discussion-based, and lab-based instruction. At least one-third of class sessions will be hands-on. We will discuss relevant book chapters and journal articles, and work with simulated and real data using the Python programming language (no prior programming experience necessary) as we survey some selected areas of research at the intersection of computational modeling and social behavior. These selected topics will span a broad set of social psychological abilities including (1) learning from and for others, (2) learning about others, and (3) social influence on decision-making and mental states. Rhoads, S. A. & Gan, L. (2022). Computational models of human social behavior and neuroscience - An open educational course and Jupyter Book to advance computational training. Journal of Open Source Education, 5(47), 146. https://doi.org/10.21105/jose.00146
This book was written with the goal of introducing researchers and students in a variety of research fields to the intersection of data science and neuroimaging. This book reflects our own experience of doing research at the intersection of data science and neuroimaging and it is based on our experience working with students and collaborators who come from a variety of backgrounds and have a variety of reasons for wanting to use data science approaches in their work. The tools and ideas that we chose to write about are all tools and ideas that we have used in some way in our own research. Many of them are tools that we use on a daily basis in our work. This was important to us for a few reasons: the first is that we want to teach people things that we ourselves find useful. Second, it allowed us to write the book with a focus on solving specific analysis tasks. For example, in many of the chapters you will see that we walk you through ideas while implementing them in code, and with data. We believe that this is a good way to learn about data analysis, because it provides a connecting thread from scientific questions through the data and its representation to implementing specific answers to these questions. Finally, we find these ideas compelling and fruitful. That’s why we were drawn to them in the first place. We hope that our enthusiasm about the ideas and tools described in this book will be infectious enough to convince the readers of their value.
This lecture focuses on how the immune system can target and attack the nervous system to produce autoimmune responses that may result in diseases such as multiple sclerosis, neuromyelitis and lupus cerebritis manifested by motor, sensory, and cognitive impairments. Despite the fact that the brain is an immune-privileged site, autoreactive lymphocytes producing proinflammatory cytokines can cause active brain inflammation, leading to myelin and axonal loss.
This lecture will highlight our current understanding and recent developments in the field of neurodegenerative disease research, as well as the future of diagnostics and treatment of neurodegenerative diseases
This lecture provides an overview of depression (epidemiology and course of the disorder), clinical presentation, somatic co-morbidity, and treatment options.
How genetics can contribute to our understanding of psychiatric phenotypes.
The lecture focuses on rationale for employing neuroimaging methods for movement disorders
An overview of some of the essential concepts in neuropharmacology (e.g. receptor binding, agonism, antagonism), an introduction to pharmacodynamics and pharmacokinetics, and an overview of the drug discovery process relative to diseases of the Central Nervous System.
Audio slides presentation to accompany the paper titled: An automated pipeline for constructing personalized virtual brains from multimodal neuroimaging data. Authors: M. Schirner, S. Rothmeier, V. Jirsa, A.R. McIntosh, P. Ritter.
Tutorial on collaborating with Git and GitHub. This tutorial was part of the 2019 Neurohackademy, a 2-week hands-on summer institute in neuroimaging and data science held at the University of Washington eScience Institute.