This book was written with the goal of introducing researchers and students in a variety of research fields to the intersection of data science and neuroimaging. This book reflects our own experience of doing research at the intersection of data science and neuroimaging and it is based on our experience working with students and collaborators who come from a variety of backgrounds and have a variety of reasons for wanting to use data science approaches in their work. The tools and ideas that we chose to write about are all tools and ideas that we have used in some way in our own research. Many of them are tools that we use on a daily basis in our work. This was important to us for a few reasons: the first is that we want to teach people things that we ourselves find useful. Second, it allowed us to write the book with a focus on solving specific analysis tasks. For example, in many of the chapters you will see that we walk you through ideas while implementing them in code, and with data. We believe that this is a good way to learn about data analysis, because it provides a connecting thread from scientific questions through the data and its representation to implementing specific answers to these questions. Finally, we find these ideas compelling and fruitful. That’s why we were drawn to them in the first place. We hope that our enthusiasm about the ideas and tools described in this book will be infectious enough to convince the readers of their value.

This Jupyter Book is a series of interactive tutorials about quantitative T1 mapping, powered by qMRLab. Most figures are generated with Plot.ly – you can play with them by hovering your mouse over the data, zooming in (click and drag) and out (double click), moving the sliders, and changing the drop-down options. To view the code that was used to generate the figures in this blog post, hover your cursor in the top left corner of the frame that contains the tutorial and click the checkbox “All cells” in the popup that appears.

Jupyter Lab notebooks of these tutorials are also available through MyBinder, and inline code modification inside the Jupyter Book is provided by Thebelab. For both options, you can modify the code, change the figures, and regenerate the html that was used to create the tutorial below. This Jupyter Book also uses a Script of Scripts (SoS) kernel, allowing us to process the data using qMRLab in MATLAB/Octave and plot the figures with Plot.ly using Python, all within the same Jupyter Notebook.

This lecture introduces neuroscience concepts and methods such as fMRI, visual respones in BOLD data, and the eccentricity of visual receptive fields. 

This tutorial walks users through the creation and visualization of activation flat maps from fMRI datasets. 

This tutorial demonstrates to users the conventional preprocessing steps when working with BOLD signal datasets from fMRI. 

In this tutorial, users will learn how to create a trial-averaged BOLD response and store it in a matrix in MATLAB. 

This tutorial teaches users how to create animations of BOLD responses over time, to allow researchers and clinicians to visualize time-course activity patterns.

This tutorial demonstrates how to use MATLAB to create event-related BOLD time courses from fMRI datasets. 

In this tutorial, users learn how to compute and visualize a t-test on experimental condition differences.

This lesson introduces various methods in MATLAB useful for dealing with data generated by calcium imaging. 

This tutorial demonstrates how to use MATLAB to generate and visualize animations of calcium fluctuations over time. 

This tutorial instructs users how to use MATLAB to programmatically convert data from cells to a matrix.

In this tutorial, users will learn how to identify and remove background noise, or "blur", an important step in isolating cell bodies from image data. 

This lesson teaches users how MATLAB can be used to apply image processing techniques to identify cell bodies based on contiguity.

This tutorial demonstrates how to extract the time course of calcium activity from each clusters of neuron somata, and store the data in a MATLAB matrix.

This lesson demonstrates how to use MATLAB to implement a multivariate dimension reduction method, PCA, on time series data.

This tutorial introduces pipelines and methods to compute brain connectomes from fMRI data. With corresponding code and repositories, participants can follow along and learn how to programmatically preprocess, curate, and analyze functional and structural brain data to produce connectivity matrices. 

This is a tutorial on designing a Bayesian inference model to map belief trajectories, with emphasis on gaining familiarity with Hierarchical Gaussian Filters (HGFs).

This lesson corresponds to slides 65-90 of the PDF below. 

This lecture and tutorial focuses on measuring human functional brain networks, as well as how to account for inherent variability within those networks. 

In this lesson, you will learn about the Python project Nipype, an open-source, community-developed initiative under the umbrella of NiPy. Nipype provides a uniform interface to existing neuroimaging software and facilitates interaction between these packages within a single workflow.