Skip to main content

This lesson is a general overview of overarching concepts in neuroinformatics research, with a particular focus on clinical approaches to defining, measuring, studying, diagnosing, and treating various brain disorders. Also described are the complex, multi-level nature of brain disorders and the data associated with them, from genes and individual cells up to cortical microcircuits and whole-brain network dynamics. Given the heterogeneity of brain disorders and their underlying mechanisms, this lesson lays out a case for multiscale neuroscience data integration.

Difficulty level: Intermediate
Duration: 1:09:33
Speaker: : Sean Hill

In this tutorial on simulating whole-brain activity using Python, participants can follow along using corresponding code and repositories, learning the basics of neural oscillatory dynamics, evoked responses and EEG signals, ultimately leading to the design of a network model of whole-brain anatomical connectivity. 

Difficulty level: Intermediate
Duration: 1:16:10
Speaker: : John Griffiths

This lesson breaks down the principles of Bayesian inference and how it relates to cognitive processes and functions like learning and perception. It is then explained how cognitive models can be built using Bayesian statistics in order to investigate how our brains interface with their environment. 

This lesson corresponds to slides 1-64 in the PDF below. 

Difficulty level: Intermediate
Duration: 1:28:14

This lecture and tutorial focuses on measuring human functional brain networks, as well as how to account for inherent variability within those networks. 

Difficulty level: Intermediate
Duration: 50:44
Speaker: : Caterina Gratton

The state of the field regarding the diagnosis and treatment of major depressive disorder (MDD) is discussed. Current challenges and opportunities facing the research and clinical communities are outlined, including appropriate quantitative and qualitative analyses of the heterogeneity of biological, social, and psychiatric factors which may contribute to MDD.

Difficulty level: Beginner
Duration: 1:29:28

This lesson delves into the opportunities and challenges of telepsychiatry. While novel digital approaches to clinical research and care have the potential to improve and accelerate patient outcomes, researchers and care providers must consider new population factors, such as digital disparity. 

Difficulty level: Beginner
Duration: 1:20:28
Speaker: : Abhi Pratap

This is a continuation of the talk on the cellular mechanisms of neuronal communication, this time at the level of brain microcircuits and associated global signals like those measureable by electroencephalography (EEG). This lecture also discusses EEG biomarkers in mental health disorders, and how those cortical signatures may be simulated digitally.

Difficulty level: Intermediate
Duration: 1:11:04
Speaker: : Etay Hay

This lecture focuses on how the immune system can target and attack the nervous system to produce autoimmune responses that may result in diseases such as multiple sclerosis, neuromyelitis, and lupus cerebritis manifested by motor, sensory, and cognitive impairments. Despite the fact that the brain is an immune-privileged site, autoreactive lymphocytes producing proinflammatory cytokines can cause active brain inflammation, leading to myelin and axonal loss.

Difficulty level: Beginner
Duration: 37:36
Speaker: : Anat Achiron

This lecture will provide an overview of neuroimaging techniques and their clinical applications.

Difficulty level: Beginner
Duration: 45:29
Speaker: : Dafna Ben Bashat

This lecture picks up from the previous lesson, providing an overview of neuroimaging techniques and their clinical applications.

Difficulty level: Beginner
Duration: 41:00
Speaker: : Dafna Ben Bashat

This lesson discusses both state-of-the-art detection and prevention schema in working with neurodegenerative diseases. 

Difficulty level: Beginner
Duration: 1:02:29
Speaker: : Nir Giladi

This lecture provides an overview of depression (epidemiology and course of the disorder), clinical presentation, somatic co-morbidity, and treatment options.

Difficulty level: Beginner
Duration: 37:51

In this lesson, you will learn about how genetics can contribute to our understanding of psychiatric phenotypes.

Difficulty level: Beginner
Duration: 55:15
Speaker: : Sven Cichon

This lecture focuses on the rationale for employing neuroimaging methods for movement disorders.

Difficulty level: Beginner
Duration: 1:04:04
Speaker: : Bogdan Draganski

This lecture provides an overview of some of the essential concepts in neuropharmacology (e.g. receptor binding, agonism, antagonism), an introduction to pharmacodynamics and pharmacokinetics, and an overview of the drug discovery process relative to diseases of the central nervous system. 

Difficulty level: Beginner
Duration: 45:47

This tutorial demonstrates how to work with neuronal data using MATLAB, including actional potentials and spike counts, orientation tuing curves in visual cortex, and spatial maps of firing rates.

Difficulty level: Intermediate
Duration: 5:17
Speaker: : Mike X. Cohen

This lesson instructs users on how to import electrophysiological neural data into MATLAB, as well as how to convert spikes to a data matrix.

Difficulty level: Intermediate
Duration: 11:37
Speaker: : Mike X. Cohen

In this lesson, users will learn how to appropriately sort and bin neural spikes, allowing for the generation of a common and powerful visualization tool in neuroscience, the histogram. 

Difficulty level: Intermediate
Duration: 5:31
Speaker: : Mike X. Cohen

Followers of this lesson will learn how to compute, visualize and quantify the tuning curves of individual neurons. 

Difficulty level: Intermediate
Duration: 13:48
Speaker: : Mike X. Cohen

This lesson demonstrates how to programmatically generate a spatial map of neuronal spike counts using MATLAB.

Difficulty level: Intermediate
Duration: 12:16
Speaker: : Mike X. Cohen