The simulation of the virtual epileptic patient is presented as an example of advanced brain simulation as a translational approach to deliver improved results in clinics. The fundamentals of epilepsy are explained. On this basis, the concept of epilepsy simulation is developed. By using an iPython notebook, the detailed process of this approach is explained step by step. In the end, you are able to perform simple epilepsy simulations your own.

Learn how to simulate seizure events and epilepsy in The Virtual Brain. We will look at the paper: On the Nature of Seizure Dynamics which describes a new local model called the Epileptor, and apply this same model in The Virtual Brain. This is part 1 of 2 in a series explaining how to use the Epileptor. In this part, we focus on setting up the parameters.

The Virtual Brain is an open-source, multi-scale, multi-modal brain simulation platform. In this lesson, you get introduced to brain simulation in general and to The Virtual brain in particular. Prof. Ritter will present the newest approaches for clinical applications of The Virtual brain - that is, for stroke, epilepsy, brain tumors and Alzheimer’s disease - and show how brain simulation can improve diagnostics, therapy and understanding of neurological disease.

The concept of neural masses, an application of mean field theory, is introduced as a possible surrogate for electrophysiological signals in brain simulation. The mathematics of neural mass models and their integration to a coupled network are explained. Bifurcation analysis is presented as an important technique in the understanding of non-linear systems and as a fundamental method in the design of brain simulations. Finally, the application of the described mathematics is demonstrated in the exploration of brain stimulation regimes.

The practical usage of The Virtual brain in its graphical user interface and via python scripts is introduced. In the graphical user interface, you are guided through its data repository, simulator, phase plane exploration tool, connectivity editor, stimulus generator and the provided analyses. The implemented iPython notebooks of TVB are presented, and since they are public, can be used for further exploration of The Virtual brain.

A brief overview of the Python programming language, with an emphasis on tools relevant to data scientists. This lecture was part of the 2018 Neurohackademy, a 2-week hands-on summer institute in neuroimaging and data science held at the University of Washington eScience Institute.

Colt Steele provides a comprehensive introduction to the command line and 50 popular Linux commands.  This is a long course (nearly 5 hours) but well worth it if you are going to spend a good part of your career working from a terminal, which is likely if you are interested in flexibility, power, and reproducibility in neuroscience research.

This lesson is courtesy of freeCodeCamp.

Lecture on functional brain parcellations and a set of tutorials on bootstrap agregation of stable clusters (BASC) for fMRI brain parcellation which were part of the 2019 Neurohackademy, a 2-week hands-on summer institute in neuroimaging and data science held at the University of Washington eScience Institute.

Neuronify is an educational tool meant to create intuition for how neurons and neural networks behave. You can use it to combine neurons with different connections, just like the ones we have in our brain, and explore how changes on single cells lead to behavioral changes in important networks. Neuronify is based on an integrate-and-fire model of neurons. This is one of the simplest models of neurons that exist. It focuses on the spike timing of a neuron and ignores the details of the action potential dynamics. These neurons are modeled as simple RC circuits. When the membrane potential is above a certain threshold, a spike is generated and the voltage is reset to its resting potential. This spike then signals other neurons through its synapses.

Neuronify aims to provide a low entry point to simulation-based neuroscience.

This lecture covers the linking neuronal activity to behavior using AI-based online detection. 

As a part of NeuroHackademy 2020, Elizabeth DuPre gives a lecture on "Nilearn", a python package that provides flexible statistical and machine-learning tools for brain volumes by leveraging the scikit-learn Python toolbox for multivariate statistics.  This includes predictive modelling, classification, decoding, and connectivity analysis.

This video is courtesy of the University of Washington eScience Institute.

Estefany Suárez provides a conceptual overview of the rudiments of machine learning, including its bases in traditional statistics and the types of questions it might be applied to.

The lesson was presented in the context of the BrainHack School 2020.

Jake Vogel gives a hands-on, Jupyter-notebook-based tutorial to apply machine learning in Python to brain-imaging data.

The lesson was presented in the context of the BrainHack School 2020.

Gael Varoquaux presents some advanced machine learning algorithms for neuroimaging, while addressing some real-world considerations related to data size and type.

The lesson was presented in the context of the BrainHack School 2020.

This lesson from freeCodeCamp introduces Scikit-learn, the most widely used machine learning Python library.

Dr. Guangyu Robert Yang describes how Recurrent Neural Networks (RNNs) trained with machine learning techniques on cognitive tasks have become a widely accepted tool for neuroscientists. In comparison to traditional computational models in neuroscience, RNNs can offer substantial advantages at explaining complex behavior and neural activity patterns. Their use allows rapid generation of mechanistic hypotheses for cognitive computations. RNNs further provide a natural way to flexibly combine bottom-up biological knowledge with top-down computational goals into network models. However, early works of this approach are faced with fundamental challenges. In this talk, Dr. Guangyu Robert Yang discusses some of these challenges, and several recent steps that we took to partly address them and to build next-generation RNN models for cognitive neuroscience.​

In this presentation by the OHBM OpenScienceSIG, Tom Shaw and Steffen Bollmann cover how containers can be useful for running the same software on different platforms and sharing analysis pipelines with other researchers. They demonstrate how to build docker containers from scratch, using Neurodocker, and cover how to use containers on an HPC with singularity.

Serving as good refresher, Shawn Grooms explains the maths and logic concepts that are important for programmers to understand, including sets, propositional logic, conditional statements, and more.

This compilation is courtesy of freeCodeCamp.

Linear algebra is the branch of mathematics concerning linear equations such as linear functions and their representations through matrices and vector spaces. As such, it underlies a huge variety of analyses in the neurosciences.  This lesson provides a useful refresher which will facilitate the use of Matlab, Octave, and various matrix-manipulation and machine-learning software.

This lesson was created by RootMath.

An introduction to data management, manipulation, visualization, and analysis for neuroscience. Students will learn scientific programming in Python, and use this to work with example data from areas such as cognitive-behavioral research, single-cell recording, EEG, and structural and functional MRI. Basic signal processing techniques including filtering are covered. The course includes a Jupyter Notebook and video tutorials.