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In this lesson, you will learn about the ionic basis of the action potential, including the Hodgkin-Huxley model.

Difficulty level: Beginner
Duration: 28:29
Speaker: : Carl Petersen

This lesson delves into the specifics of how action potentials propagate through individual neurons.

Difficulty level: Beginner
Duration: 23:16
Speaker: : Carl Petersen

In this lesson, you will learn about neurotransmitter release in the presynaptic specialization.

Difficulty level: Beginner
Duration: 21:36
Speaker: : Carl Petersen

This lesson covers synaptic modulation through diffusing neurotransmitters.

Difficulty level: Beginner
Duration: 23:00
Speaker: : Carl Petersen

This lecture gives an overview of glutamatergic transmission.

Difficulty level: Beginner
Duration: 28:53
Speaker: : Carl Petersen

This lesson discusses glutamate release after an action potential, and the resulting post-synaptic potentials. 

Difficulty level: Beginner
Duration: 29:35
Speaker: : Carl Petersen

In this lesson, you will learn about glutamatergic excitatory neuronal circuits.

Difficulty level: Beginner
Duration: 28:36
Speaker: : Carl Petersen

This lesson gives an overview of neurons' dendritic spines and their function.

Difficulty level: Beginner
Duration: 21:31
Speaker: : Carl Petersen

This lecture provides an introduction GABAergic inhibition and its receptors.

Difficulty level: Beginner
Duration: 25:18
Speaker: : Carl Petersen

This lesson takes a closer look at GABA_A receptor mediated fast inhibition.

Difficulty level: Beginner
Duration: 18:51
Speaker: : Carl Petersen

This lecture focuses on how benzodiazepines act on GABA_A receptors.

Difficulty level: Beginner
Duration: 14:05
Speaker: : Carl Petersen

This lesson discusses long-range inhibitory connections in the brain, with examples from three different systems.

Difficulty level: Beginner
Duration: 19:05
Speaker: : Carl Petersen

This lecture provides an introduction to the application of genetic testing in neurodevelopmental disorders.

Difficulty level: Beginner
Duration: 37:47

This lesson describes the fundamentals of genomics, from central dogma to design and implementation of GWAS, to the computation, analysis, and interpretation of polygenic risk scores. 

Difficulty level: Intermediate
Duration: 1:28:16
Speaker: : Dan Felsky

This is a hands-on tutorial on PLINK, the open source whole genome association analysis toolset. The aims of this tutorial are to teach users how to perform basic quality control on genetic datasets, as well as to identify and understand GWAS summary statistics. 

Difficulty level: Intermediate
Duration: 1:27:18
Speaker: : Dan Felsky

This is a tutorial on using the open-source software PRSice to calculate a set of polygenic risk scores (PRS) for a study sample. Users will also learn how to read PRS into R, visualize distributions, and perform basic association analyses. 

Difficulty level: Intermediate
Duration: 1:53:34
Speaker: : Dan Felsky

This lesson contains the slides (pptx) of a lecture discussing the necessary concepts and tools for taking into account population stratification and admixture in the context of genome-wide association studies (GWAS). The free-access software Tractor and its advantages in GWAS are also discussed. 

Difficulty level: Intermediate
Duration:
Speaker: : Dan Felsky

This lesson is an overview of transcriptomics, from fundamental concepts of the central dogma and RNA sequencing at the single-cell level, to how genetic expression underlies diversity in cell phenotypes. 

Difficulty level: Intermediate
Duration: 1:29:08

This is a tutorial introducing participants to the basics of RNA-sequencing data and how to analyze its features using Seurat. 

Difficulty level: Intermediate
Duration: 1:19:17
Speaker: : Sonny Chen

This tutorial demonstrates how to perform cell-type deconvolution in order to estimate how proportions of cell-types in the brain change in response to various conditions. While these techniques may be useful in addressing a wide range of scientific questions, this tutorial will focus on the cellular changes associated with major depression (MDD). 

Difficulty level: Intermediate
Duration: 1:15:14
Speaker: : Keon Arbabi