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This lecture provides an introduction to optogenetics, a biological technique to control the activity of neurons or other cell types with light.

Difficulty level: Beginner
Duration: 39:34
Speaker: : Adam Packer

This primer on optogenetics primer discusses how to manipulate neuronal populations with light at millisecond resolution and offers possible applications such as curing the blind and "playing the piano" with cortical neurons.

Difficulty level: Beginner
Duration: 59:06
Speaker: : Clay Reid

This talk gives an overview of the Human Brain Project, a 10-year endeavour putting in place a cutting-edge research infrastructure that will allow scientific and industrial researchers to advance our knowledge in the fields of neuroscience, computing, and brain-related medicine.

Difficulty level: Intermediate
Duration: 24:52
Speaker: : Katrin Amunts

This lecture gives an introduction to the European Academy of Neurology, its recent achievements and ambitions.

Difficulty level: Intermediate
Duration: 21:57
Speaker: : Paul Boon

This talk enumerates the challenges regarding data accessibility and reusability inherent in the current scientific publication system, and discusses novel approaches to these challenges, such as the EBRAINS Live Papers platform. 

Difficulty level: Beginner
Duration: 18:08
Speaker: : Andrew Davison

This lesson aims to define computational neuroscience in general terms, while providing specific examples of highly successful computational neuroscience projects. 

Difficulty level: Beginner
Duration: 59:21
Speaker: : Alla Borisyuk

This lesson covers membrane potential of neurons, and how parameters around this potential have direct consequences on cellular communication at both the individual and population level. 

Difficulty level: Beginner
Duration: 28:08
Speaker: : Carl Petersen

In this lesson you will learn about neurons' ability to generate signals called action potentials, and biophysics of voltage-gated ion channels.

Difficulty level: Beginner
Duration: 27:47
Speaker: : Carl Petersen

This lesson discusses voltage-gating kinetics of sodium and potassium channels.

Difficulty level: Beginner
Duration: 19:20
Speaker: : Carl Petersen

In this lesson, you will learn about the ionic basis of the action potential, including the Hodgkin-Huxley model.

Difficulty level: Beginner
Duration: 28:29
Speaker: : Carl Petersen

This lesson delves into the specifics of how action potentials propagate through individual neurons.

Difficulty level: Beginner
Duration: 23:16
Speaker: : Carl Petersen

This lesson discusses long-range inhibitory connections in the brain, with examples from three different systems.

Difficulty level: Beginner
Duration: 19:05
Speaker: : Carl Petersen
Course:

An introduction to data management, manipulation, visualization, and analysis for neuroscience. Students will learn scientific programming in Python, and use this to work with example data from areas such as cognitive-behavioral research, single-cell recording, EEG, and structural and functional MRI. Basic signal processing techniques including filtering are covered. The course includes a Jupyter Notebook and video tutorials.

 

Difficulty level: Beginner
Duration: 1:09:16
Speaker: : Aaron J. Newman

This lesson discusses both state-of-the-art detection and prevention schema in working with neurodegenerative diseases. 

Difficulty level: Beginner
Duration: 1:02:29
Speaker: : Nir Giladi

This lecture focuses on how the immune system can target and attack the nervous system to produce autoimmune responses that may result in diseases such as multiple sclerosis, neuromyelitis, and lupus cerebritis manifested by motor, sensory, and cognitive impairments. Despite the fact that the brain is an immune-privileged site, autoreactive lymphocytes producing proinflammatory cytokines can cause active brain inflammation, leading to myelin and axonal loss.

Difficulty level: Beginner
Duration: 37:36
Speaker: : Anat Achiron

This lecture provides an introduction to the application of genetic testing in neurodevelopmental disorders.

Difficulty level: Beginner
Duration: 37:47

This lesson describes the fundamentals of genomics, from central dogma to design and implementation of GWAS, to the computation, analysis, and interpretation of polygenic risk scores. 

Difficulty level: Intermediate
Duration: 1:28:16
Speaker: : Dan Felsky

This is a hands-on tutorial on PLINK, the open source whole genome association analysis toolset. The aims of this tutorial are to teach users how to perform basic quality control on genetic datasets, as well as to identify and understand GWAS summary statistics. 

Difficulty level: Intermediate
Duration: 1:27:18
Speaker: : Dan Felsky

This is a tutorial on using the open-source software PRSice to calculate a set of polygenic risk scores (PRS) for a study sample. Users will also learn how to read PRS into R, visualize distributions, and perform basic association analyses. 

Difficulty level: Intermediate
Duration: 1:53:34
Speaker: : Dan Felsky

This lesson contains the slides (pptx) of a lecture discussing the necessary concepts and tools for taking into account population stratification and admixture in the context of genome-wide association studies (GWAS). The free-access software Tractor and its advantages in GWAS are also discussed. 

Difficulty level: Intermediate
Duration:
Speaker: : Dan Felsky