The simulation of the virtual epileptic patient is presented as an example of advanced brain simulation as a translational approach to deliver improved results in clinics. The fundamentals of epilepsy are explained. On this basis, the concept of epilepsy simulation is developed. By using an iPython notebook, the detailed process of this approach is explained step by step. In the end, you are able to perform simple epilepsy simulations your own.
Explore how to setup an epileptic seizure simulation with the TVB graphical user interface. This lesson will show you how to program the epileptor model in the brain network to simulate a epileptic seizure originating in the hippocampus. It will also show how to upload and view mouse connectivity data, as well as give a short introduction to the python script interface of TVB.
Learn how to simulate seizure events and epilepsy in The Virtual Brain. We will look at the paper: On the Nature of Seizure Dynamics which describes a new local model called the Epileptor, and apply this same model in The Virtual Brain. This is part 1 of 2 in a series explaining how to use the Epileptor. In this part, we focus on setting up the parameters.
This primer on optogenetics primer discusses how to manipulate neuronal populations with light at millisecond resolution and offers possible applications such as curing the blind and "playing the piano" with cortical neurons.
A basic introduction to clinical presentation of schizophrenia, its etiology, and current treatment options.
Introduction to the course Cellular Mechanisms of Brain Function.
Introduction to the course Cellular Mechanisms of Brain Function.
Ion channels and the movement of ions across the cell membrane.
Action potential initiation and propagation.
Synaptic transmission and neurotransmitters
This lecture covers NeuronUnit, a library that builds upon SciUnit and integrates with several existing neuroinformatics resources to support validating single-neuron models using data gathered by neurophysiologists.
An introduction to the NeuroElectro project, which aims to organize information on cellular neurophysiology. Speaker: Shreejoy Tripathy
Simultaneously recorded neurons in non-human primates coordinate their spiking activity in a sequential manner that mirrors the dominant wave propagation directions of the local field potentials.
This talk covers statistical analysis of spike train data, the modeling approach GLM, and the problem of assessing neural synchrony.
This talk covers statistical methods for characterizing neural population responses and extracting structure from high-dimensional neural data.
This presentation covers research to understand the activity of single neurons and populations of neurons in the visual system.
An overview of some of the essential concepts in neuropharmacology (e.g. receptor binding, agonism, antagonism), an introduction to pharmacodynamics and pharmacokinetics, and an overview of the drug discovery process relative to diseases of the Central Nervous System.
From the retina to the superior colliculus, the lateral geniculate nucleus into primary visual cortex and beyond, this lecture gives a tour of the mammalian visual system highlighting the Nobel-prize winning discoveries of Hubel & Wiesel.
From Universal Turing Machines to McCulloch-Pitts and Hopfield associative memory networks, this lecture explains what is meant by computation.
In an overview of the structure of the mammalian neocortex, this lecture explains how the mammalian cortex is organized in a hierarchy, describing the columnar principle and canonical microcircuits