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This talk gives an overview of the Human Brain Project, a 10-year endeavour putting in place a cutting-edge research infrastructure that will allow scientific and industrial researchers to advance our knowledge in the fields of neuroscience, computing, and brain-related medicine.

Difficulty level: Intermediate
Duration: 24:52
Speaker: : Katrin Amunts

This lecture gives an introduction to the European Academy of Neurology, its recent achievements and ambitions.

Difficulty level: Intermediate
Duration: 21:57
Speaker: : Paul Boon

This talk enumerates the challenges regarding data accessibility and reusability inherent in the current scientific publication system, and discusses novel approaches to these challenges, such as the EBRAINS Live Papers platform. 

Difficulty level: Beginner
Duration: 18:08
Speaker: : Andrew Davison

This lesson aims to define computational neuroscience in general terms, while providing specific examples of highly successful computational neuroscience projects. 

Difficulty level: Beginner
Duration: 59:21
Speaker: : Alla Borisyuk

This lesson covers membrane potential of neurons, and how parameters around this potential have direct consequences on cellular communication at both the individual and population level. 

Difficulty level: Beginner
Duration: 28:08
Speaker: : Carl Petersen

In this lesson you will learn about neurons' ability to generate signals called action potentials, and biophysics of voltage-gated ion channels.

Difficulty level: Beginner
Duration: 27:47
Speaker: : Carl Petersen

This lesson discusses voltage-gating kinetics of sodium and potassium channels.

Difficulty level: Beginner
Duration: 19:20
Speaker: : Carl Petersen

In this lesson, you will learn about the ionic basis of the action potential, including the Hodgkin-Huxley model.

Difficulty level: Beginner
Duration: 28:29
Speaker: : Carl Petersen

This lesson delves into the specifics of how action potentials propagate through individual neurons.

Difficulty level: Beginner
Duration: 23:16
Speaker: : Carl Petersen

This lesson discusses long-range inhibitory connections in the brain, with examples from three different systems.

Difficulty level: Beginner
Duration: 19:05
Speaker: : Carl Petersen
Course:

An introduction to data management, manipulation, visualization, and analysis for neuroscience. Students will learn scientific programming in Python, and use this to work with example data from areas such as cognitive-behavioral research, single-cell recording, EEG, and structural and functional MRI. Basic signal processing techniques including filtering are covered. The course includes a Jupyter Notebook and video tutorials.

 

Difficulty level: Beginner
Duration: 1:09:16
Speaker: : Aaron J. Newman

While the previous lesson in the Neuro4ML course dealt with the mechanisms involved in individual synapses, this lesson discusses how synapses and their neurons' firing patterns may change over time. 

Difficulty level: Intermediate
Duration: 4:48
Speaker: : Marcus Ghosh

In this lesson, you will learn about how machine learners and computational neuroscientists design and build models of neuronal synapses. 

Difficulty level: Intermediate
Duration: 8:59
Speaker: : Dan Goodman

How does the brain learn? This lecture discusses the roles of development and adult plasticity in shaping functional connectivity.

Difficulty level: Beginner
Duration: 1:08:45
Speaker: : Clay Reid

This lesson goes into the mechanisms behind changes in synaptic function created by learning.

Difficulty level: Beginner
Duration: 27:07
Speaker: : Carl Petersen

This lecture explains the concept of federated analysis in the context of medical data, associated challenges. The lecture also presents an example of hospital federations via the Medical Informatics Platform.

Difficulty level: Intermediate
Duration: 19:15
Speaker: : Yannis Ioannidis

This lesson continues with the second workshop on reproducible science, focusing on additional open source tools for researchers and data scientists, such as the R programming language for data science, as well as associated tools like RStudio and R Markdown. Additionally, users are introduced to Python and iPython notebooks, Google Colab, and are given hands-on tutorials on how to create a Binder environment, as well as various containers in Docker and Singularity.

Difficulty level: Beginner
Duration: 1:16:04

This lesson contains both a lecture and a tutorial component. The lecture (0:00-20:03 of YouTube video) discusses both the need for intersectional approaches in healthcare as well as the impact of neglecting intersectionality in patient populations. The lecture is followed by a practical tutorial in both Python and R on how to assess intersectional bias in datasets. Links to relevant code and data are found below. 

Difficulty level: Beginner
Duration: 52:26

This is a hands-on tutorial on PLINK, the open source whole genome association analysis toolset. The aims of this tutorial are to teach users how to perform basic quality control on genetic datasets, as well as to identify and understand GWAS summary statistics. 

Difficulty level: Intermediate
Duration: 1:27:18
Speaker: : Dan Felsky

This is a tutorial on using the open-source software PRSice to calculate a set of polygenic risk scores (PRS) for a study sample. Users will also learn how to read PRS into R, visualize distributions, and perform basic association analyses. 

Difficulty level: Intermediate
Duration: 1:53:34
Speaker: : Dan Felsky