This lecture covers an introduction to neuroinformatics and its subfields, the content of the short course and future neuroinformatics applications.
Ion channels and the movement of ions across the cell membrane.
Action potentials, and biophysics of voltage-gated ion channels.
Voltage-gating kinetics of sodium and potassium channels.
The ionic basis of the action potential, including the Hodgkin Huxley model.
Action potential initiation and propagation.
Long-range inhibitory connections in the brain, with examples from three different systems.
Introduction to neurons, synaptic transmission, and ion channels.
2nd part of the lecture. Introduction to cell receptors and signalling cascades
Introduction to the types of glial cells, homeostasis (influence of cerebral blood flow and influence on neurons), insulation and protection of axons (myelin sheath; nodes of Ranvier), microglia and reactions of the CNS to injury.
Introduction to the origin and differentiation of myelinating cell types, molecular mechanisms defining onset and progression of myelination, demyelination and remyelination after injury.
This lecture covers: integrating information within a network, modulating and controlling networks, functions and dysfunctions of hippocampal networks, and the integrative network controlling sleep and arousal.
This lecture focuses on the comprehension of nociception and pain sensation. It highlights how the somatosensory system and different molecular partners are involved in nociception and how nociception and pain sensation are studied in rodents and humans and the development of pain therapy.
JupyterHub is a simple, highly extensible, multi-user system for managing per-user Jupyter Notebook servers, designed for research groups or classes. This lecture covers deploying JupyterHub on a single server, as well as deploying with Docker using GitHub for authentication.