This primer on optogenetics primer discusses how to manipulate neuronal populations with light at millisecond resolution and offers possible applications such as curing the blind and "playing the piano" with cortical neurons.
Ion channels and the movement of ions across the cell membrane.
Action potentials, and biophysics of voltage-gated ion channels.
Voltage-gating kinetics of sodium and potassium channels.
The ionic basis of the action potential, including the Hodgkin Huxley model.
Action potential initiation and propagation.
Long-range inhibitory connections in the brain, with examples from three different systems.
The "connectome" is a term, coined in the past decade, that has been used to describe more than one phenomenon in neuroscience. This lecture explains the basics of structural connections at the micro-, meso- and macroscopic scales.
How does the brain learn? This lecture discusses the roles of development and adult plasticity in shaping functional connectivity.
An overview of some of the essential concepts in neuropharmacology (e.g. receptor binding, agonism, antagonism), an introduction to pharmacodynamics and pharmacokinetics, and an overview of the drug discovery process relative to diseases of the Central Nervous System.
This lecture covers describing and characterizing an input-output relationship.
This tutorial talks about how to upload and version your data in OpenNeuro.org
This tutorial shows how to share your data in OpenNeuro.org
This tutorial shows how to run analysis in OpenNeuro.org
Inferring results from incomplete data
Finding parameter values, confidence intervals.
Methods for estimating parameters.
Measuring the correspondece between data and model.
How to choose useful variables.
Common problems in statistical modelling.