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This lecture focuses on ontologies for clinical neurosciences.

Difficulty level: Intermediate
Duration: 21:54

This lecture focuses on how the immune system can target and attack the nervous system to produce autoimmune responses that may result in diseases such as multiple sclerosis, neuromyelitis, and lupus cerebritis manifested by motor, sensory, and cognitive impairments. Despite the fact that the brain is an immune-privileged site, autoreactive lymphocytes producing proinflammatory cytokines can cause active brain inflammation, leading to myelin and axonal loss.

Difficulty level: Beginner
Duration: 37:36
Speaker: : Anat Achiron

This lesson provides an overview of how to construct computational pipelines for neurophysiological data using DataJoint.

Difficulty level: Beginner
Duration: 17:37
Speaker: : Dimitri Yatsenko

This lesson delves into the the structure of one of the brain's most elemental computational units, the neuron, and how said structure influences computational neural network models. 

Difficulty level: Intermediate
Duration: 6:33
Speaker: : Marcus Ghosh

Following the previous lesson on neuronal structure, this lesson discusses neuronal function, particularly focusing on spike triggering and propogation. 

Difficulty level: Intermediate
Duration: 6:58
Speaker: : Marcus Ghosh

This lesson goes over the basic mechanisms of neural synapses, the space between neurons where signals may be transmitted. 

Difficulty level: Intermediate
Duration: 7:03
Speaker: : Marcus Ghosh

While the previous lesson in the Neuro4ML course dealt with the mechanisms involved in individual synapses, this lesson discusses how synapses and their neurons' firing patterns may change over time. 

Difficulty level: Intermediate
Duration: 4:48
Speaker: : Marcus Ghosh

Whereas the previous two lessons described the biophysical and signalling properties of individual neurons, this lesson describes properties of those units when part of larger networks. 

Difficulty level: Intermediate
Duration: 6:00
Speaker: : Marcus Ghosh

This lesson covers the ionic basis of the action potential, including the Hodgkin-Huxley model. 

Difficulty level: Beginner
Duration: 28:29
Speaker: : Carl Petersen

This lesson provides an introduction to the myriad forms of cellular mechanisms whicn underpin healthy brain function and communication. 

Difficulty level: Beginner
Duration: 12:20
Speaker: : Carl Petersen

In this lesson you will learn about the ionic basis of the action potential, including the Hodgkin-Huxley model. 

Difficulty level: Beginner
Duration: 28:29
Speaker: : Carl Petersen

This lesson provides an introduction to the course Cellular Mechanisms of Brain Function.

Difficulty level: Beginner
Duration: 12:20
Speaker: : Carl Petersen

This lesson covers membrane potential of neurons, and how parameters around this potential have direct consequences on cellular communication at both the individual and population level. 

Difficulty level: Beginner
Duration: 28:08
Speaker: : Carl Petersen

This lesson covers the spatiotemporal dynamics of the membrane potential.

Difficulty level: Beginner
Duration: 19:14
Speaker: : Carl Petersen

In this lesson you will learn about neurons' ability to generate signals called action potentials, and biophysics of voltage-gated ion channels.

Difficulty level: Beginner
Duration: 27:47
Speaker: : Carl Petersen

This lesson discusses voltage-gating kinetics of sodium and potassium channels.

Difficulty level: Beginner
Duration: 19:20
Speaker: : Carl Petersen

In this lesson, you will learn about the ionic basis of the action potential, including the Hodgkin-Huxley model.

Difficulty level: Beginner
Duration: 28:29
Speaker: : Carl Petersen

This lesson delves into the specifics of how action potentials propagate through individual neurons.

Difficulty level: Beginner
Duration: 23:16
Speaker: : Carl Petersen

In this lesson, you will learn about neurotransmitter release in the presynaptic specialization.

Difficulty level: Beginner
Duration: 21:36
Speaker: : Carl Petersen

This lesson covers synaptic modulation through diffusing neurotransmitters.

Difficulty level: Beginner
Duration: 23:00
Speaker: : Carl Petersen