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The Mouse Phenome Database (MPD) provides access to primary experimental trait data, genotypic variation, protocols and analysis tools for mouse genetic studies. Data are contributed by investigators worldwide and represent a broad scope of phenotyping endpoints and disease-related traits in naïve mice and those exposed to drugs, environmental agents or other treatments. MPD ensures rigorous curation of phenotype data and supporting documentation using relevant ontologies and controlled vocabularies. As a repository of curated and integrated data, MPD provides a means to access/re-use baseline data, as well as allows users to identify sensitized backgrounds for making new mouse models with genome editing technologies, analyze trait co-inheritance, benchmark assays in their own laboratories, and many other research applications. MPD’s primary source of funding is NIDA. For this reason, a majority of MPD data is neuro- and behavior-related.

Difficulty level: Beginner
Duration: 55:36
Speaker: : Elissa Chesler
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Lecture on the most important concepts in software engineering

Difficulty level: Beginner
Duration: 32:59
Speaker: : Jeff Muller
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Introductory presentation on how data science can help with scientific reproducibility.

Difficulty level: Beginner
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Speaker: : Michel Dumontier
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Introduction to the Mathematics chapter of Datalabcc's "Foundations in Data Science" series.

Difficulty level: Beginner
Duration: 2:53
Speaker: : Barton Poulson
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Primer on elementary algebra

Difficulty level: Beginner
Duration: 3:03
Speaker: : Barton Poulson
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Primer on linear algebra

Difficulty level: Beginner
Duration: 5:38
Speaker: : Barton Poulson
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Primer on systems of linear equations

Difficulty level: Beginner
Duration: 5:24
Speaker: : Barton Poulson
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Primer on calculus

Difficulty level: Beginner
Duration: 4:17
Speaker: : Barton Poulson
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How calculus relates to optimization

Difficulty level: Beginner
Duration: 8:43
Speaker: : Barton Poulson
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Big O notation

Difficulty level: Beginner
Duration: 5:19
Speaker: : Barton Poulson
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Basics of probability.

Difficulty level: Beginner
Duration: 7:33
Speaker: : Barton Poulson
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This lecture covers computational principles that growth cones employ to detect and respond to environmental chemotactic gradients, focusing particularly on growth cone shape dynamics.

Difficulty level: Intermediate
Duration: 26:12
Speaker: : Geoff Goodhill
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In this lecture you will learn that in developing mouse somatosensory cortex, endogenous Btbd3 translocate to the cell nucleus in response to neuronal activity and oriented primary dendrites toward active axons in the barrel hollow.

Difficulty level: Intermediate
Duration: 27:32
Speaker: : Tomomi Shimogori
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In this presentation, the speaker describes some of their recent efforts to characterize the transcriptome of the developing human brain, and and introduction to the BrainSpan project.

Difficulty level: Intermediate
Duration: 30:45
Speaker: : Nenad Sestan
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How does the brain learn? This lecture discusses the roles of development and adult plasticity in shaping functional connectivity.

Difficulty level: Beginner
Duration: 1:08:45
Speaker: : Clay Reid
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2nd part of the lecture. Introduction to cell receptors and signalling cascades

Difficulty level: Beginner
Duration: 41:38
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GABAergic interneurons and local inhibition on the circuit level.

Difficulty level: Beginner
Duration: 16:27
Speaker: : Carl Petersen
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The "connectome" is a term, coined in the past decade, that has been used to describe more than one phenomenon in neuroscience. This lecture explains the basics of structural connections at the micro-, meso- and macroscopic scales.

Difficulty level: Beginner
Duration: 1:13:16
Speaker: : Clay Reid
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The Human Connectome Project aims to provide an unparalleled compilation of neural data, an interface to graphically navigate this data and the opportunity to achieve never before realized conclusions about the living human brain.

Difficulty level: Advanced
Duration: 59:06
Speaker: : Jennifer Elam
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This lecture focuses on how the immune system can target and attack the nervous system to produce autoimmune responses that may result in diseases such as multiple sclerosis, neuromyelitis and lupus cerebritis manifested by motor, sensory, and cognitive impairments. Despite the fact that the brain is an immune-privileged site, autoreactive lymphocytes producing proinflammatory cytokines can cause active brain inflammation, leading to myelin and axonal loss.

Difficulty level: Beginner
Duration: 37:36
Speaker: : Anat Achiron