In this lesson, you will learn about the ionic basis of the action potential, including the Hodgkin-Huxley model.
This lesson delves into the specifics of how action potentials propagate through individual neurons.
In this lesson, you will learn about neurotransmitter release in the presynaptic specialization.
This lesson covers synaptic modulation through diffusing neurotransmitters.
This lecture gives an overview of glutamatergic transmission.
This lesson discusses glutamate release after an action potential, and the resulting post-synaptic potentials.
In this lesson, you will learn about glutamatergic excitatory neuronal circuits.
This lesson gives an overview of neurons' dendritic spines and their function.
This lecture provides an introduction GABAergic inhibition and its receptors.
This lesson takes a closer look at GABA_A receptor mediated fast inhibition.
This lecture focuses on how benzodiazepines act on GABA_A receptors.
This lesson discusses long-range inhibitory connections in the brain, with examples from three different systems.
In this lesson, you will learn about GABAergic interneurons and local inhibition on the circuit level.
This lecture provides an introduction to the application of genetic testing in neurodevelopmental disorders.
This lesson describes the fundamentals of genomics, from central dogma to design and implementation of GWAS, to the computation, analysis, and interpretation of polygenic risk scores.
This is a hands-on tutorial on PLINK, the open source whole genome association analysis toolset. The aims of this tutorial are to teach users how to perform basic quality control on genetic datasets, as well as to identify and understand GWAS summary statistics.
This is a tutorial on using the open-source software PRSice to calculate a set of polygenic risk scores (PRS) for a study sample. Users will also learn how to read PRS into R, visualize distributions, and perform basic association analyses.
This lesson contains the slides (pptx) of a lecture discussing the necessary concepts and tools for taking into account population stratification and admixture in the context of genome-wide association studies (GWAS). The free-access software Tractor and its advantages in GWAS are also discussed.
This lesson is an overview of transcriptomics, from fundamental concepts of the central dogma and RNA sequencing at the single-cell level, to how genetic expression underlies diversity in cell phenotypes.
This is a tutorial introducing participants to the basics of RNA-sequencing data and how to analyze its features using Seurat.