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This lesson is a general overview of overarching concepts in neuroinformatics research, with a particular focus on clinical approaches to defining, measuring, studying, diagnosing, and treating various brain disorders. Also described are the complex, multi-level nature of brain disorders and the data associated with them, from genes and individual cells up to cortical microcircuits and whole-brain network dynamics. Given the heterogeneity of brain disorders and their underlying mechanisms, this lesson lays out a case for multiscale neuroscience data integration.

Difficulty level: Intermediate
Duration: 1:09:33
Speaker: : Sean Hill

This lesson gives an in-depth introduction of ethics in the field of artificial intelligence, particularly in the context of its impact on humans and public interest. As the healthcare sector becomes increasingly affected by the implementation of ever stronger AI algorithms, this lecture covers key interests which must be protected going forward, including privacy, consent, human autonomy, inclusiveness, and equity. 

Difficulty level: Beginner
Duration: 1:22:06
Speaker: : Daniel Buchman

This lesson describes a definitional framework for fairness and health equity in the age of the algorithm. While acknowledging the impressive capability of machine learning to positively affect health equity, this talk outlines potential (and actual) pitfalls which come with such powerful tools, ultimately making the case for collaborative, interdisciplinary, and transparent science as a way to operationalize fairness in health equity. 

Difficulty level: Beginner
Duration: 1:06:35
Speaker: : Laura Sikstrom

This is a continuation of the talk on the cellular mechanisms of neuronal communication, this time at the level of brain microcircuits and associated global signals like those measureable by electroencephalography (EEG). This lecture also discusses EEG biomarkers in mental health disorders, and how those cortical signatures may be simulated digitally.

Difficulty level: Intermediate
Duration: 1:11:04
Speaker: : Etay Hay

This lesson describes the principles underlying functional magnetic resonance imaging (fMRI), diffusion-weighted imaging (DWI), tractography, and parcellation. These tools and concepts are explained in a broader context of neural connectivity and mental health. 

Difficulty level: Intermediate
Duration: 1:47:22

This lesson goes over the basic mechanisms of neural synapses, the space between neurons where signals may be transmitted. 

Difficulty level: Intermediate
Duration: 7:03
Speaker: : Marcus Ghosh

This lesson describes spike timing-dependent plasticity (STDP), a biological process that adjusts the strength of connections between neurons in the brain, and how one can implement or mimic this process in a computational model. You will also find links for practical exercises at the bottom of this page. 

Difficulty level: Intermediate
Duration: 12:50
Speaker: : Dan Goodman

This lesson explores how researchers try to understand neural networks, particularly in the case of observing neural activity. 

Difficulty level: Intermediate
Duration: 8:20
Speaker: : Marcus Ghosh

This video gives a brief introduction to Neuro4ML's lessons on neuromorphic computing - the use of specialized hardware which either directly mimics brain function or is inspired by some aspect of the way the brain computes. 

Difficulty level: Intermediate
Duration: 3:56
Speaker: : Dan Goodman

In this lesson, you will learn in more detail about neuromorphic computing, that is, non-standard computational architectures that mimic some aspect of the way the brain works. 

Difficulty level: Intermediate
Duration: 10:08
Speaker: : Dan Goodman

This video provides a very quick introduction to some of the neuromorphic sensing devices, and how they offer unique, low-power applications.

Difficulty level: Intermediate
Duration: 2:37
Speaker: : Dan Goodman

This lesson discusses a gripping neuroscientific question: why have neurons developed the discrete action potential, or spike, as a principle method of communication? 

Difficulty level: Intermediate
Duration: 9:34
Speaker: : Dan Goodman

This lecture will provide an overview of neuroimaging techniques and their clinical applications.

Difficulty level: Beginner
Duration: 45:29
Speaker: : Dafna Ben Bashat

This lecture picks up from the previous lesson, providing an overview of neuroimaging techniques and their clinical applications.

Difficulty level: Beginner
Duration: 41:00
Speaker: : Dafna Ben Bashat

This lesson discusses both state-of-the-art detection and prevention schema in working with neurodegenerative diseases. 

Difficulty level: Beginner
Duration: 1:02:29
Speaker: : Nir Giladi

This lesson provides a basic introduction to clinical presentation of schizophrenia, its etiology, and current treatment options.

Difficulty level: Beginner
Duration: 51:49

This lecture focuses on the rationale for employing neuroimaging methods for movement disorders.

Difficulty level: Beginner
Duration: 1:04:04
Speaker: : Bogdan Draganski

This lecture provides an overview of some of the essential concepts in neuropharmacology (e.g. receptor binding, agonism, antagonism), an introduction to pharmacodynamics and pharmacokinetics, and an overview of the drug discovery process relative to diseases of the central nervous system. 

Difficulty level: Beginner
Duration: 45:47

This lecture gives an introduction to the types of glial cells, homeostasis (influence of cerebral blood flow and influence on neurons), insulation and protection of axons (myelin sheath; nodes of Ranvier), microglia and reactions of the CNS to injury.

Difficulty level: Beginner
Duration: 40:32

This lesson gives an introductory presentation on how data science can help with scientific reproducibility.

Difficulty level: Beginner
Duration:
Speaker: : Michel Dumontier