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This lesson delves into the human nervous system and the immense cellular, connectomic, and functional sophistication therein. 

Difficulty level: Intermediate
Duration: 8:41
Speaker: : Marcus Ghosh

This lesson describes spike timing-dependent plasticity (STDP), a biological process that adjusts the strength of connections between neurons in the brain, and how one can implement or mimic this process in a computational model. You will also find links for practical exercises at the bottom of this page. 

Difficulty level: Intermediate
Duration: 12:50
Speaker: : Dan Goodman

 In this lesson, you will learn about some of the many methods to train spiking neural networks (SNNs) with either no attempt to use gradients, or only use gradients in a limited or constrained way. 

Difficulty level: Intermediate
Duration: 5:14
Speaker: : Dan Goodman

In this lesson, you will learn how to train spiking neural networks (SNNs) with a surrogate gradient method. 

Difficulty level: Intermediate
Duration: 11:23
Speaker: : Dan Goodman

In this lesson, you will hear about some of the open issues in the field of neuroscience, as well as a discussion about whether neuroscience works, and how can we know?

Difficulty level: Intermediate
Duration: 6:54
Speaker: : Marcus Ghosh

This lecture focuses on how the immune system can target and attack the nervous system to produce autoimmune responses that may result in diseases such as multiple sclerosis, neuromyelitis, and lupus cerebritis manifested by motor, sensory, and cognitive impairments. Despite the fact that the brain is an immune-privileged site, autoreactive lymphocytes producing proinflammatory cytokines can cause active brain inflammation, leading to myelin and axonal loss.

Difficulty level: Beginner
Duration: 37:36
Speaker: : Anat Achiron

This lecture provides an overview of depression (epidemiology and course of the disorder), clinical presentation, somatic co-morbidity, and treatment options.

Difficulty level: Beginner
Duration: 37:51

This lecture provides an overview of some of the essential concepts in neuropharmacology (e.g. receptor binding, agonism, antagonism), an introduction to pharmacodynamics and pharmacokinetics, and an overview of the drug discovery process relative to diseases of the central nervous system. 

Difficulty level: Beginner
Duration: 45:47

This lesson gives an introduction to simple spiking neuron models.

Difficulty level: Beginner
Duration: 48 Slides
Speaker: : Zubin Bhuyan

This lesson provides an introduction to simple spiking neuron models.

Difficulty level: Beginner
Duration: 48 Slides
Speaker: : Zubin Bhuyan

This lesson gives a primer to project management in a scientific context, with a particular neuroinformatic case study. 

Difficulty level: Beginner
Duration: 19:06
Speaker: : Kelly Shen

In this lesson, you will hear about the current challenges regarding data management, as well as policies and resources aimed to address them. 

Difficulty level: Beginner
Duration: 18:13
Speaker: : Mojib Javadi

This lesson provides an overview of how to manage relationships in a research context, while highlighting the need for effective communication at various levels.

Difficulty level: Beginner
Duration:
Speaker: : Helena Ledmyr

This presentation accompanies the paper entitled: An automated pipeline for constructing personalized virtual brains from multimodal neuroimaging data (see link below to download publication). 

Difficulty level: Beginner
Duration: 4:56

This lecture on model types introduces the advantages of modeling, provide examples of different model types, and explain what modeling is all about. 

Difficulty level: Beginner
Duration: 27:48
Speaker: : Gunnar Blohm

This lecture focuses on how to get from a scientific question to a model using concrete examples. We will present a 10-step practical guide on how to succeed in modeling. This lecture contains links to 2 tutorials, lecture/tutorial slides, suggested reading list, and 3 recorded Q&A sessions.

Difficulty level: Beginner
Duration: 29:52
Speaker: : Megan Peters

This lecture formalizes modeling as a decision process that is constrained by a precise problem statement and specific model goals. We provide real-life examples on how model building is usually less linear than presented in Modeling Practice I

Difficulty level: Beginner
Duration: 22:51
Speaker: : Gunnar Blohm

This lecture focuses on the purpose of model fitting, approaches to model fitting, model fitting for linear models, and how to assess the quality and compare model fits. We will present a 10-step practical guide on how to succeed in modeling. 

Difficulty level: Beginner
Duration: 26:46
Speaker: : Jan Drugowitsch

This lecture summarizes the concepts introduced in Model Fitting I and adds two additional concepts: 1) MLE is a frequentist way of looking at the data and the model, with its own limitations. 2) Side-by-side comparisons of bootstrapping and cross-validation.

Difficulty level: Beginner
Duration: 38.17
Speaker: : Kunlin Wei

This lecture provides an overview of the generalized linear models (GLM) course, originally a part of the Neuromatch Academy (NMA), an interactive online summer school held in 2020. NMA provided participants with experiences spanning from hands-on modeling experience to meta-science interpretation skills across just about everything that could reasonably be included in the label "computational neuroscience". 

Difficulty level: Beginner
Duration: 33:58
Speaker: : Cristina Savin