This lesson is a general overview of overarching concepts in neuroinformatics research, with a particular focus on clinical approaches to defining, measuring, studying, diagnosing, and treating various brain disorders. Also described are the complex, multi-level nature of brain disorders and the data associated with them, from genes and individual cells up to cortical microcircuits and whole-brain network dynamics. Given the heterogeneity of brain disorders and their underlying mechanisms, this lesson lays out a case for multiscale neuroscience data integration.
The state of the field regarding the diagnosis and treatment of major depressive disorder (MDD) is discussed. Current challenges and opportunities facing the research and clinical communities are outlined, including appropriate quantitative and qualitative analyses of the heterogeneity of biological, social, and psychiatric factors which may contribute to MDD.
This lesson continues with the second workshop on reproducible science, focusing on additional open source tools for researchers and data scientists, such as the R programming language for data science, as well as associated tools like RStudio and R Markdown. Additionally, users are introduced to Python and iPython notebooks, Google Colab, and are given hands-on tutorials on how to create a Binder environment, as well as various containers in Docker and Singularity.
This lesson gives an in-depth introduction of ethics in the field of artificial intelligence, particularly in the context of its impact on humans and public interest. As the healthcare sector becomes increasingly affected by the implementation of ever stronger AI algorithms, this lecture covers key interests which must be protected going forward, including privacy, consent, human autonomy, inclusiveness, and equity.
This lesson delves into the opportunities and challenges of telepsychiatry. While novel digital approaches to clinical research and care have the potential to improve and accelerate patient outcomes, researchers and care providers must consider new population factors, such as digital disparity.
This is a continuation of the talk on the cellular mechanisms of neuronal communication, this time at the level of brain microcircuits and associated global signals like those measureable by electroencephalography (EEG). This lecture also discusses EEG biomarkers in mental health disorders, and how those cortical signatures may be simulated digitally.
In this lesson, you will learn about the current challenges facing the integration of machine learning and neuroscience.
While the previous lesson in the Neuro4ML course dealt with the mechanisms involved in individual synapses, this lesson discusses how synapses and their neurons' firing patterns may change over time.
This lesson discusses a gripping neuroscientific question: why have neurons developed the discrete action potential, or spike, as a principle method of communication?
This lecture picks up from the previous lesson, providing an overview of neuroimaging techniques and their clinical applications.
This lesson discusses both state-of-the-art detection and prevention schema in working with neurodegenerative diseases.
This lesson provides a basic introduction to clinical presentation of schizophrenia, its etiology, and current treatment options.
This lecture focuses on the rationale for employing neuroimaging methods for movement disorders.
This lesson gives an introductory presentation on how data science can help with scientific reproducibility.
This lesson provides a brief overview of the Python programming language, with an emphasis on tools relevant to data scientists.
This tutorial covers the fundamentals of collaborating with Git and GitHub.
The lecture provides an overview of the core skills and practical solutions required to practice reproducible research.
This lecture covers FAIR atlases, including their background and construction, as well as how they can be created in line with the FAIR principles.
This lecture covers how to make modeling workflows FAIR by working through a practical example, dissecting the steps within the workflow, and detailing the tools and resources used at each step.
This lecture discusses the FAIR principles as they apply to electrophysiology data and metadata, the building blocks for community tools and standards, platforms and grassroots initiatives, and the challenges therein.