This lesson is a general overview of overarching concepts in neuroinformatics research, with a particular focus on clinical approaches to defining, measuring, studying, diagnosing, and treating various brain disorders. Also described are the complex, multi-level nature of brain disorders and the data associated with them, from genes and individual cells up to cortical microcircuits and whole-brain network dynamics. Given the heterogeneity of brain disorders and their underlying mechanisms, this lesson lays out a case for multiscale neuroscience data integration.
This lesson continues with the second workshop on reproducible science, focusing on additional open source tools for researchers and data scientists, such as the R programming language for data science, as well as associated tools like RStudio and R Markdown. Additionally, users are introduced to Python and iPython notebooks, Google Colab, and are given hands-on tutorials on how to create a Binder environment, as well as various containers in Docker and Singularity.
This lesson describes the principles underlying functional magnetic resonance imaging (fMRI), diffusion-weighted imaging (DWI), tractography, and parcellation. These tools and concepts are explained in a broader context of neural connectivity and mental health.
This lesson breaks down the principles of Bayesian inference and how it relates to cognitive processes and functions like learning and perception. It is then explained how cognitive models can be built using Bayesian statistics in order to investigate how our brains interface with their environment.
This lesson corresponds to slides 1-64 in the PDF below.
This lesson delves into the the structure of one of the brain's most elemental computational units, the neuron, and how said structure influences computational neural network models.
This lesson goes over the basic mechanisms of neural synapses, the space between neurons where signals may be transmitted.
While the previous lesson in the Neuro4ML course dealt with the mechanisms involved in individual synapses, this lesson discusses how synapses and their neurons' firing patterns may change over time.
Whereas the previous two lessons described the biophysical and signalling properties of individual neurons, this lesson describes properties of those units when part of larger networks.
This lesson goes over some examples of how machine learners and computational neuroscientists go about designing and building neural network models inspired by biological brain systems.
This lesson delves into the human nervous system and the immense cellular, connectomic, and functional sophistication therein.
This lesson explores how researchers try to understand neural networks, particularly in the case of observing neural activity.
In this lesson, you will learn in more detail about neuromorphic computing, that is, non-standard computational architectures that mimic some aspect of the way the brain works.
This video provides a very quick introduction to some of the neuromorphic sensing devices, and how they offer unique, low-power applications.
In this lesson, you will hear about some of the open issues in the field of neuroscience, as well as a discussion about whether neuroscience works, and how can we know?
This lecture will provide an overview of neuroimaging techniques and their clinical applications.
This lecture gives an introduction to the types of glial cells, homeostasis (influence of cerebral blood flow and influence on neurons), insulation and protection of axons (myelin sheath; nodes of Ranvier), microglia and reactions of the CNS to injury.
This lecture provides an introduction to the principal of anatomical organization of neural systems in the human brain and spinal cord that mediate sensation, integrate signals, and motivate behavior.
This lecture focuses on the comprehension of nociception and pain sensation, highlighting how the somatosensory system and different molecular partners are involved in nociception.
This lesson provides a brief overview of the Python programming language, with an emphasis on tools relevant to data scientists.
This lecture provides an introduction to the Brain Imaging Data Structure (BIDS), a standard for organizing human neuroimaging datasets.