This lesson is a general overview of overarching concepts in neuroinformatics research, with a particular focus on clinical approaches to defining, measuring, studying, diagnosing, and treating various brain disorders. Also described are the complex, multi-level nature of brain disorders and the data associated with them, from genes and individual cells up to cortical microcircuits and whole-brain network dynamics. Given the heterogeneity of brain disorders and their underlying mechanisms, this lesson lays out a case for multiscale neuroscience data integration.

This lesson breaks down the principles of Bayesian inference and how it relates to cognitive processes and functions like learning and perception. It is then explained how cognitive models can be built using Bayesian statistics in order to investigate how our brains interface with their environment. 

This lesson corresponds to slides 1-64 in the PDF below. 

This lecture covers a lot of post-war developments in the science of the mind, focusing first on the cognitive revolution, and concluding with living machines.

In this lesson, you will learn about the current challenges facing the integration of machine learning and neuroscience. 

This lesson delves into the the structure of one of the brain's most elemental computational units, the neuron, and how said structure influences computational neural network models. 

In this lesson you will learn how machine learners and neuroscientists construct abstract computational models based on various neurophysiological signalling properties. 

Whereas the previous two lessons described the biophysical and signalling properties of individual neurons, this lesson describes properties of those units when part of larger networks. 

This lesson goes over some examples of how machine learners and computational neuroscientists go about designing and building neural network models inspired by biological brain systems. 

This lesson describes spike timing-dependent plasticity (STDP), a biological process that adjusts the strength of connections between neurons in the brain, and how one can implement or mimic this process in a computational model. You will also find links for practical exercises at the bottom of this page. 

 In this lesson, you will learn about some of the many methods to train spiking neural networks (SNNs) with either no attempt to use gradients, or only use gradients in a limited or constrained way. 

In this lesson, you will learn how to train spiking neural networks (SNNs) with a surrogate gradient method. 

This video gives a brief introduction to Neuro4ML's lessons on neuromorphic computing - the use of specialized hardware which either directly mimics brain function or is inspired by some aspect of the way the brain computes. 

In this lesson, you will learn in more detail about neuromorphic computing, that is, non-standard computational architectures that mimic some aspect of the way the brain works. 

This video provides a very quick introduction to some of the neuromorphic sensing devices, and how they offer unique, low-power applications.

In this lesson, you will hear about some of the open issues in the field of neuroscience, as well as a discussion about whether neuroscience works, and how can we know?

This lecture gives an introduction to the types of glial cells, homeostasis (influence of cerebral blood flow and influence on neurons), insulation and protection of axons (myelin sheath; nodes of Ranvier), microglia and reactions of the CNS to injury.

This lesson gives an introduction to simple spiking neuron models.

This lesson provides an introduction to simple spiking neuron models.

This lesson discusses FAIR principles and methods currently in development for assessing FAIRness.

This lesson gives a primer to project management in a scientific context, with a particular neuroinformatic case study.