The state of the field regarding the diagnosis and treatment of major depressive disorder (MDD) is discussed. Current challenges and opportunities facing the research and clinical communities are outlined, including appropriate quantitative and qualitative analyses of the heterogeneity of biological, social, and psychiatric factors which may contribute to MDD.

This lesson continues with the second workshop on reproducible science, focusing on additional open source tools for researchers and data scientists, such as the R programming language for data science, as well as associated tools like RStudio and R Markdown. Additionally, users are introduced to Python and iPython notebooks, Google Colab, and are given hands-on tutorials on how to create a Binder environment, as well as various containers in Docker and Singularity.

This lesson delves into the opportunities and challenges of telepsychiatry. While novel digital approaches to clinical research and care have the potential to improve and accelerate patient outcomes, researchers and care providers must consider new population factors, such as digital disparity. 

This lesson describes the principles underlying functional magnetic resonance imaging (fMRI), diffusion-weighted imaging (DWI), tractography, and parcellation. These tools and concepts are explained in a broader context of neural connectivity and mental health. 

In this lesson, you will learn about the current challenges facing the integration of machine learning and neuroscience. 

This lesson goes over the basic mechanisms of neural synapses, the space between neurons where signals may be transmitted. 

This lesson describes spike timing-dependent plasticity (STDP), a biological process that adjusts the strength of connections between neurons in the brain, and how one can implement or mimic this process in a computational model. You will also find links for practical exercises at the bottom of this page. 

This lesson explores how researchers try to understand neural networks, particularly in the case of observing neural activity. 

This lesson discusses a gripping neuroscientific question: why have neurons developed the discrete action potential, or spike, as a principle method of communication? 

This lecture will provide an overview of neuroimaging techniques and their clinical applications.

This lesson provides a basic introduction to clinical presentation of schizophrenia, its etiology, and current treatment options.

This lecture provides an overview of some of the essential concepts in neuropharmacology (e.g. receptor binding, agonism, antagonism), an introduction to pharmacodynamics and pharmacokinetics, and an overview of the drug discovery process relative to diseases of the central nervous system. 

This lecture gives an introduction to the types of glial cells, homeostasis (influence of cerebral blood flow and influence on neurons), insulation and protection of axons (myelin sheath; nodes of Ranvier), microglia and reactions of the CNS to injury.

This lesson gives an introductory presentation on how data science can help with scientific reproducibility.

This lesson discusses FAIR principles and methods currently in development for assessing FAIRness.

This lesson provides a brief overview of the Python programming language, with an emphasis on tools relevant to data scientists.

This lecture provides an introduction to the Brain Imaging Data Structure (BIDS), a standard for organizing human neuroimaging datasets.

This tutorial covers the fundamentals of collaborating with Git and GitHub.

This lecture presents an overview of functional brain parcellations, as well as a set of tutorials on bootstrap agregation of stable clusters (BASC) for fMRI brain parcellation.

The lecture provides an overview of the core skills and practical solutions required to practice reproducible research.