This lesson is a general overview of overarching concepts in neuroinformatics research, with a particular focus on clinical approaches to defining, measuring, studying, diagnosing, and treating various brain disorders. Also described are the complex, multi-level nature of brain disorders and the data associated with them, from genes and individual cells up to cortical microcircuits and whole-brain network dynamics. Given the heterogeneity of brain disorders and their underlying mechanisms, this lesson lays out a case for multiscale neuroscience data integration.
The state of the field regarding the diagnosis and treatment of major depressive disorder (MDD) is discussed. Current challenges and opportunities facing the research and clinical communities are outlined, including appropriate quantitative and qualitative analyses of the heterogeneity of biological, social, and psychiatric factors which may contribute to MDD.
This is the first of two workshops on reproducibility in science, during which participants are introduced to concepts of FAIR and open science. After discussing the definition of and need for FAIR science, participants are walked through tutorials on installing and using Github and Docker, the powerful, open-source tools for versioning and publishing code and software, respectively.
This lesson contains both a lecture and a tutorial component. The lecture (0:00-20:03 of YouTube video) discusses both the need for intersectional approaches in healthcare as well as the impact of neglecting intersectionality in patient populations. The lecture is followed by a practical tutorial in both Python and R on how to assess intersectional bias in datasets. Links to relevant code and data are found below.
This lesson delves into the opportunities and challenges of telepsychiatry. While novel digital approaches to clinical research and care have the potential to improve and accelerate patient outcomes, researchers and care providers must consider new population factors, such as digital disparity.
This lesson is an overview of transcriptomics, from fundamental concepts of the central dogma and RNA sequencing at the single-cell level, to how genetic expression underlies diversity in cell phenotypes.
This lesson explains the fundamental principles of neuronal communication, such as neuronal spiking, membrane potentials, and cellular excitability, and how these electrophysiological features of the brain may be modelled and simulated digitally.
This lesson describes the principles underlying functional magnetic resonance imaging (fMRI), diffusion-weighted imaging (DWI), tractography, and parcellation. These tools and concepts are explained in a broader context of neural connectivity and mental health.
This lecture covers the emergence of cognitive science after the Second World War as an interdisciplinary field for studying the mind, with influences from anthropology, cybernetics, and artificial intelligence.
This lecture covers different perspectives on the study of the mental, focusing on the difference between Mind and Brain.
Introduction of the Foundations of Machine Learning in Python course - Day 01.
High-Performance Computing and Analytics Lab, University of Bonn
Optimization for machine learning - Day 02 lecture of the Foundations of Machine Learning in Python course.
High-Performance Computing and Analytics Lab, University of Bonn
Linear Algebra for Machine Learning - Day 03 lecture of the Foundations of Machine Learning in Python course.
High-Performance Computing and Analytics Lab, University of Bonn
Support Vector Machines - Day 06 lecture of the Foundations of Machine Learning in Python course.
High-Performance Computing and Analytics Lab, University of Bonn
Decision Trees and Random Forests - Day 07 lecture of the Foundations of Machine Learning in Python course.
High-Performance Computing and Analytics Lab, University of Bonn
Clustering and Density Estimation - Day 08 lecture of the Foundations of Machine Learning in Python course.
High-Performance Computing and Analytics Lab, University of Bonn
Dimensionality Reduction - Day 09 lecture of the Foundations of Machine Learning in Python course.
High-Performance Computing and Analytics Lab, University of Bonn
Introduction to Neural Networks - Day 10 lecture of the Foundations of Machine Learning in Python course.
High-Performance Computing and Analytics Lab, University of Bonn
Introduction to Convolutional Neural Networks - Day 11 lecture of the Foundations of Machine Learning in Python course.
High-Performance Computing and Analytics Lab, University of Bonn
Initialization, Optimization, and Regularization - Day 12 lecture of the Foundations of Machine Learning in Python course.
High-Performance Computing and Analytics Lab, University of Bonn