This lesson discusses FAIR principles and methods currently in development for assessing FAIRness.
This is a continuation of the talk on the cellular mechanisms of neuronal communication, this time at the level of brain microcircuits and associated global signals like those measureable by electroencephalography (EEG). This lecture also discusses EEG biomarkers in mental health disorders, and how those cortical signatures may be simulated digitally.
This lesson provides an introduction to the lifecycle of EEG/ERP data, describing the various phases through which these data pass, from collection to publication.
In this lesson you will learn about experimental design for EEG acquisition, as well as the first phases of the EEG/ERP data lifecycle.
This lesson provides an overview of the current regulatory measures in place regarding experimental data security and privacy.
In this lesson, you will learn the appropriate methods for collection of both data and associated metadata during EEG experiments.
This lesson goes over methods for managing EEG/ERP data after it has been collected, from annotation to publication.
In this final lesson of the course, you will learn broadly about EEG signal processing, as well as specific applications which make this kind of brain signal valuable to researchers and clinicians.
This lecture contains an overview of the Australian Electrophysiology Data Analytics Platform (AEDAPT), how it works, how to scale it, and how it fits into the FAIR ecosystem.
This lecture covers FAIR atlases, including their background and construction, as well as how they can be created in line with the FAIR principles.
This lesson gives an introductory presentation on how data science can help with scientific reproducibility.
This lecture covers how to make modeling workflows FAIR by working through a practical example, dissecting the steps within the workflow, and detailing the tools and resources used at each step.
This lesson delves into the the structure of one of the brain's most elemental computational units, the neuron, and how said structure influences computational neural network models.
This lesson goes over the basic mechanisms of neural synapses, the space between neurons where signals may be transmitted.
While the previous lesson in the Neuro4ML course dealt with the mechanisms involved in individual synapses, this lesson discusses how synapses and their neurons' firing patterns may change over time.
Whereas the previous two lessons described the biophysical and signalling properties of individual neurons, this lesson describes properties of those units when part of larger networks.
This lecture provides an overview of some of the essential concepts in neuropharmacology (e.g. receptor binding, agonism, antagonism), an introduction to pharmacodynamics and pharmacokinetics, and an overview of the drug discovery process relative to diseases of the central nervous system.
This lesson continues with the second workshop on reproducible science, focusing on additional open source tools for researchers and data scientists, such as the R programming language for data science, as well as associated tools like RStudio and R Markdown. Additionally, users are introduced to Python and iPython notebooks, Google Colab, and are given hands-on tutorials on how to create a Binder environment, as well as various containers in Docker and Singularity.
This lesson contains both a lecture and a tutorial component. The lecture (0:00-20:03 of YouTube video) discusses both the need for intersectional approaches in healthcare as well as the impact of neglecting intersectionality in patient populations. The lecture is followed by a practical tutorial in both Python and R on how to assess intersectional bias in datasets. Links to relevant code and data are found below.
This lesson is an overview of transcriptomics, from fundamental concepts of the central dogma and RNA sequencing at the single-cell level, to how genetic expression underlies diversity in cell phenotypes.