This lecture provides an overview of depression (epidemiology and course of the disorder), clinical presentation, somatic co-morbidity, and treatment options.
Overview of the Braintorm package for analyzing extracellular electrophysiology, including preprocessing, spike sorting, trial alignment, and spectrotemporal decomposition
Overview of the CaImAn package, and demonstration of usage with NWB
Overview of the SpikeInterface package, including demonstration of data loading, preprocessing, spike sorting, and comparison of spike sorters
Overview of the NWBWidgets package, including coverage of different data types, and information for building custom widgets within this framework
This lecture focuses on how the immune system can target and attack the nervous system to produce autoimmune responses that may result in diseases such as multiple sclerosis, neuromyelitis and lupus cerebritis manifested by motor, sensory, and cognitive impairments. Despite the fact that the brain is an immune-privileged site, autoreactive lymphocytes producing proinflammatory cytokines can cause active brain inflammation, leading to myelin and axonal loss.