This lesson is a general overview of overarching concepts in neuroinformatics research, with a particular focus on clinical approaches to defining, measuring, studying, diagnosing, and treating various brain disorders. Also described are the complex, multi-level nature of brain disorders and the data associated with them, from genes and individual cells up to cortical microcircuits and whole-brain network dynamics. Given the heterogeneity of brain disorders and their underlying mechanisms, this lesson lays out a case for multiscale neuroscience data integration.

This lesson breaks down the principles of Bayesian inference and how it relates to cognitive processes and functions like learning and perception. It is then explained how cognitive models can be built using Bayesian statistics in order to investigate how our brains interface with their environment. 

This lesson corresponds to slides 1-64 in the PDF below. 

Whereas the previous two lessons described the biophysical and signalling properties of individual neurons, this lesson describes properties of those units when part of larger networks. 

This lesson goes over some examples of how machine learners and computational neuroscientists go about designing and building neural network models inspired by biological brain systems. 

This lecture presents an overview of functional brain parcellations, as well as a set of tutorials on bootstrap agregation of stable clusters (BASC) for fMRI brain parcellation.

Neuronify is an educational tool meant to create intuition for how neurons and neural networks behave. You can use it to combine neurons with different connections, just like the ones we have in our brain, and explore how changes on single cells lead to behavioral changes in important networks. Neuronify is based on an integrate-and-fire model of neurons. This is one of the simplest models of neurons that exist. It focuses on the spike timing of a neuron and ignores the details of the action potential dynamics. These neurons are modeled as simple RC circuits. When the membrane potential is above a certain threshold, a spike is generated and the voltage is reset to its resting potential. This spike then signals other neurons through its synapses.

Neuronify aims to provide a low entry point to simulation-based neuroscience.

This lecture goes into detailed description of how to process workflows in the virtual research environment (VRE), including approaches for standardization, metadata, containerization, and constructing and maintaining scientific pipelines. 

This lesson provides an overview of how to conceptualize, design, implement, and maintain neuroscientific pipelines in via the cloud-based computational reproducibility platform Code Ocean. 

This lesson provides an overview of how to construct computational pipelines for neurophysiological data using DataJoint.

This talk describes approaches to maintaining integrated workflows and data management schema, taking advantage of the many open source, collaborative platforms already existing.

This hands-on tutorial walks you through DataJoint platform, highlighting features and schema which can be used to build robost neuroscientific pipelines. 

In this third and final hands-on tutorial from the Research Workflows for Collaborative Neuroscience workshop, you will learn about workflow orchestration using open source tools like DataJoint and Flyte. 

This lecture provides a detailed description of how to incorporate HED annotation into your neuroimaging data pipeline. 

This lecture describes how to build research workflows, including a demonstrate using DataJoint Elements to build data pipelines.

This lesson gives an introductory presentation on how data science can help with scientific reproducibility.

This lecture covers how to make modeling workflows FAIR by working through a practical example, dissecting the steps within the workflow, and detailing the tools and resources used at each step.

This lesson gives an in-depth introduction of ethics in the field of artificial intelligence, particularly in the context of its impact on humans and public interest. As the healthcare sector becomes increasingly affected by the implementation of ever stronger AI algorithms, this lecture covers key interests which must be protected going forward, including privacy, consent, human autonomy, inclusiveness, and equity. 

This is a continuation of the talk on the cellular mechanisms of neuronal communication, this time at the level of brain microcircuits and associated global signals like those measureable by electroencephalography (EEG). This lecture also discusses EEG biomarkers in mental health disorders, and how those cortical signatures may be simulated digitally.

This lecture picks up from the previous lesson, providing an overview of neuroimaging techniques and their clinical applications.

This lesson provides a basic introduction to clinical presentation of schizophrenia, its etiology, and current treatment options.