This lesson provides an overview of the database of Genotypes and Phenotypes (dbGaP), which was developed to archive and distribute the data and results from studies that have investigated the interaction of genotype and phenotype in humans.

This lecture covers a wide range of aspects regarding neuroinformatics and data governance, describing both their historical developments and current trajectories. Particular tools, platforms, and standards to make your research more FAIR are also discussed.

Introduction of the Foundations of Machine Learning in Python course - Day 01.

High-Performance Computing and Analytics Lab, University of Bonn

Optimization for machine learning - Day 02 lecture of the Foundations of Machine Learning in Python course.

High-Performance Computing and Analytics Lab, University of Bonn

Linear Algebra for Machine Learning - Day 03 lecture of the Foundations of Machine Learning in Python course.

High-Performance Computing and Analytics Lab, University of Bonn

Support Vector Machines -  Day 06 lecture of the  Foundations of Machine Learning in Python course.

High-Performance Computing and Analytics Lab, University of Bonn

Decision Trees and Random Forests -  Day 07 lecture of the  Foundations of Machine Learning in Python course.

High-Performance Computing and Analytics Lab, University of Bonn

Clustering and Density Estimation -  Day 08 lecture of the  Foundations of Machine Learning in Python course.

High-Performance Computing and Analytics Lab, University of Bonn

Dimensionality Reduction -  Day 09 lecture of the  Foundations of Machine Learning in Python course.

High-Performance Computing and Analytics Lab, University of Bonn

Introduction to Neural Networks -  Day 10 lecture of the  Foundations of Machine Learning in Python course.

High-Performance Computing and Analytics Lab, University of Bonn

Introduction to Convolutional Neural Networks  -  Day 11 lecture of the  Foundations of Machine Learning in Python course.

High-Performance Computing and Analytics Lab, University of Bonn

Initialization, Optimization, and Regularization  -  Day 12 lecture of the  Foundations of Machine Learning in Python course.

High-Performance Computing and Analytics Lab, University of Bonn

U-Nets for medical Image-Segmentation  -  Day 13 lecture of the  Foundations of Machine Learning in Python course.

High-Performance Computing and Analytics Lab, University of Bonn

Sequence Processing -  Day 15 lecture of the  Foundations of Machine Learning in Python course.

High-Performance Computing and Analytics Lab, University of Bonn

The state of the field regarding the diagnosis and treatment of major depressive disorder (MDD) is discussed. Current challenges and opportunities facing the research and clinical communities are outlined, including appropriate quantitative and qualitative analyses of the heterogeneity of biological, social, and psychiatric factors which may contribute to MDD.

This lesson delves into the opportunities and challenges of telepsychiatry. While novel digital approaches to clinical research and care have the potential to improve and accelerate patient outcomes, researchers and care providers must consider new population factors, such as digital disparity. 

This lesson provides a basic introduction to clinical presentation of schizophrenia, its etiology, and current treatment options.

This lesson is a general overview of overarching concepts in neuroinformatics research, with a particular focus on clinical approaches to defining, measuring, studying, diagnosing, and treating various brain disorders. Also described are the complex, multi-level nature of brain disorders and the data associated with them, from genes and individual cells up to cortical microcircuits and whole-brain network dynamics. Given the heterogeneity of brain disorders and their underlying mechanisms, this lesson lays out a case for multiscale neuroscience data integration.

This tutorial demonstrates how to perform cell-type deconvolution in order to estimate how proportions of cell-types in the brain change in response to various conditions. While these techniques may be useful in addressing a wide range of scientific questions, this tutorial will focus on the cellular changes associated with major depression (MDD). 

This lesson explains the fundamental principles of neuronal communication, such as neuronal spiking, membrane potentials, and cellular excitability, and how these electrophysiological features of the brain may be modelled and simulated digitally.