This lesson describes the fundamentals of genomics, from central dogma to design and implementation of GWAS, to the computation, analysis, and interpretation of polygenic risk scores.
This is a hands-on tutorial on PLINK, the open source whole genome association analysis toolset. The aims of this tutorial are to teach users how to perform basic quality control on genetic datasets, as well as to identify and understand GWAS summary statistics.
This is a tutorial on using the open-source software PRSice to calculate a set of polygenic risk scores (PRS) for a study sample. Users will also learn how to read PRS into R, visualize distributions, and perform basic association analyses.
This lesson contains the slides (pptx) of a lecture discussing the necessary concepts and tools for taking into account population stratification and admixture in the context of genome-wide association studies (GWAS). The free-access software Tractor and its advantages in GWAS are also discussed.
This lesson is an overview of transcriptomics, from fundamental concepts of the central dogma and RNA sequencing at the single-cell level, to how genetic expression underlies diversity in cell phenotypes.
This is a tutorial introducing participants to the basics of RNA-sequencing data and how to analyze its features using Seurat.
This tutorial demonstrates how to perform cell-type deconvolution in order to estimate how proportions of cell-types in the brain change in response to various conditions. While these techniques may be useful in addressing a wide range of scientific questions, this tutorial will focus on the cellular changes associated with major depression (MDD).
This lecture covers a lot of post-war developments in the science of the mind, focusing first on the cognitive revolution, and concluding with living machines.
In this workshop talk, you will receive a tour of the Code Ocean ScienceOps Platform, a centralized cloud workspace for all teams.
This talk describes approaches to maintaining integrated workflows and data management schema, taking advantage of the many open source, collaborative platforms already existing.
In this third and final hands-on tutorial from the Research Workflows for Collaborative Neuroscience workshop, you will learn about workflow orchestration using open source tools like DataJoint and Flyte.
This lesson provides an introduction to the DataLad, a free and open source distributed data management system that keeps track of your data, creates structure, ensures reproducibility, supports collaboration, and integrates with widely used data infrastructure.
This lesson introduces several open science tools like Docker and Apptainer which can be used to develop portable and reproducible software environments.
In this hands-on session, you will learn how to explore and work with DataLad datasets, containers, and structures using Jupyter notebooks.
This lecture provides a detailed description of how to incorporate HED annotation into your neuroimaging data pipeline.
This lecture covers a wide range of aspects regarding neuroinformatics and data governance, describing both their historical developments and current trajectories. Particular tools, platforms, and standards to make your research more FAIR are also discussed.
This lecture describes how to build research workflows, including a demonstrate using DataJoint Elements to build data pipelines.
Introduction of the Foundations of Machine Learning in Python course - Day 01.
High-Performance Computing and Analytics Lab, University of Bonn
Optimization for machine learning - Day 02 lecture of the Foundations of Machine Learning in Python course.
High-Performance Computing and Analytics Lab, University of Bonn
Linear Algebra for Machine Learning - Day 03 lecture of the Foundations of Machine Learning in Python course.
High-Performance Computing and Analytics Lab, University of Bonn