Overview of the content for Day 1 of this course.
Best practices: the tips and tricks on how to get your Miniscope to work and how to get your experiments off the ground.
This talk delves into challenges and opportunities of Miniscope design, seeking the optimal balance between scale and function.
Attendees of this talk will learn aobut computational imaging systems and associated pipelines, as well as open-source software solutions supporting miniscope use.
This talk covers the present state and future directions of calcium imaging data analysis, particularly in the context of one-photon vs two-photon approaches.
In this talk, results from rodent experimentation using in vivo imaging are presented, demonstrating how the monitoring of neural ensembles may reveal patterns of learning during spatial tasks.
How to start processing the raw imaging data generated with a Miniscope, including developing a usable pipeline and demoing the Minion pipeline.
The direction of miniature microscopes, including both MetaCell and other groups.
Overview of the content for Day 2 of this course.
Summary and closing remarks for this three-day course.
This hands-on tutorial explains how to run your own Minion session in the MetaCell cloud using jupityr notebooks.
This lecture covers infrared LED oblique illumination for studying neuronal circuits in in vitro block-preparations of the spinal cord and brain stem.
This lecture covers the application of diffusion MRI for clinical and preclinical studies.
This lecture provides an introduction to the application of genetic testing in neurodevelopmental disorders.
This lesson is a general overview of overarching concepts in neuroinformatics research, with a particular focus on clinical approaches to defining, measuring, studying, diagnosing, and treating various brain disorders. Also described are the complex, multi-level nature of brain disorders and the data associated with them, from genes and individual cells up to cortical microcircuits and whole-brain network dynamics. Given the heterogeneity of brain disorders and their underlying mechanisms, this lesson lays out a case for multiscale neuroscience data integration.
This lesson gives an in-depth introduction of ethics in the field of artificial intelligence, particularly in the context of its impact on humans and public interest. As the healthcare sector becomes increasingly affected by the implementation of ever stronger AI algorithms, this lecture covers key interests which must be protected going forward, including privacy, consent, human autonomy, inclusiveness, and equity.
This lesson describes the fundamentals of genomics, from central dogma to design and implementation of GWAS, to the computation, analysis, and interpretation of polygenic risk scores.
This is a hands-on tutorial on PLINK, the open source whole genome association analysis toolset. The aims of this tutorial are to teach users how to perform basic quality control on genetic datasets, as well as to identify and understand GWAS summary statistics.
This is a tutorial on using the open-source software PRSice to calculate a set of polygenic risk scores (PRS) for a study sample. Users will also learn how to read PRS into R, visualize distributions, and perform basic association analyses.
This lesson contains the slides (pptx) of a lecture discussing the necessary concepts and tools for taking into account population stratification and admixture in the context of genome-wide association studies (GWAS). The free-access software Tractor and its advantages in GWAS are also discussed.