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In this lesson you will learn how to simulate seizure events and epilepsy in The Virtual Brain. We will look at the paper On the Nature of Seizure Dynamics, which describes a new local model called the Epileptor, and apply this same model in The Virtual Brain. This is part 1 of 2 in a series explaining how to use the Epileptor. In this part, we focus on setting up the parameters.

Difficulty level: Beginner
Duration: 4:44
Speaker: : Paul Triebkorn

In this lecture we will focus on a paper called The Virtual Epileptic Patient: Individualized whole-brain models of epilepsy spread. We will have a closer look at the equations of the epileptor model and particular the epileptogenicity index, which controls the excitability of each brain region. Subsequently, we will begin to setup the epileptogenic zone in our own brain network model with TVB.

Difficulty level: Beginner
Duration: 6:25
Speaker: : Paul Triebkorn

After introducing the local epileptor model in the previous two videos, we will now use it in a large-scale brain simulation. We again focus on the paper The Virtual Epileptic Patient: Individualized whole-brain models of epilepsy spread. Two simulations with different epileptogenicity across the network are visualized to show the difference in seizure spread across the cortex.

Difficulty level: Beginner
Duration: 6:36
Speaker: : Paul Triebkorn

This lecture gives an overview on the article Individual brain structure and modelling predict seizure propagation, in which 15 subjects with epilepsy were modelled to predict individual epileptogenic zones. With the TVB GUI we will model seizure spread and the effect of lesioning the connectome. The impact of cutting edges in the network on seizure spreading will be visualized.

Difficulty level: Beginner
Duration: 9:39
Speaker: : Paul Triebkorn

This lecture presents the Graphical (GUI) and Command Line (CLI) User Interface of TVB. Alongside with the speakers, explore and interact with all means necessary to generate, manipulate and visualize connectivity and network dynamics.

Difficulty level: Beginner
Duration: 1:02:16

This lecture presents two recent clinical case studies using TVB: stroke recovery and dementia (due to Alzheimer’s Disease (AD)). Using a multi-scale neurophysiological model based on empirical multi-modal neuroimaging data, we show how local and global biophysical parameters characterize changes in individualized patient-specific brain dynamics, predict recovery of motor function for stroke patients, and correlate with individual differences in cognition for AD patients.

Difficulty level: Intermediate
Duration: 32:11
Speaker: : Randy McIntosh

This tutorial demonstrates how to use the image processing pipeline with the HBP collab.

Difficulty level: Beginner
Duration: 5:55

This tutorial provides instruction on how to use the TVB-NEST toolbox co-simulation in HBP collab.

Difficulty level: Beginner
Duration: 3:11

In this tutorial, you will learn how to use TVB-NEST toolbox on your local computer.

Difficulty level: Beginner
Duration: 2:16

This tutorial provides instruction on how to perform multi-scale simulation of Alzheimer's disease on The Virtual Brain Simulation Platform.

Difficulty level: Beginner
Duration: 29:08

This presentation accompanies the paper entitled: An automated pipeline for constructing personalized virtual brains from multimodal neuroimaging data (see link below to download publication). 

Difficulty level: Beginner
Duration: 4:56

This lesson consists of a supplementary video for the publication: Inferring multi-scale neural mechanisms with brain network modelling.

Difficulty level: Beginner
Duration: 3:06

This demonstration walks through how to import your data into MATLAB.

Difficulty level: Beginner
Duration: 6:10
Speaker: : MATLAB®

This lesson provides instruction regarding the various factors one must consider when preprocessing data, preparing it for statistical exploration and analyses. 

Difficulty level: Beginner
Duration: 15:10
Speaker: : MATLAB®

This tutorial outlines, step by step, how to perform analysis by group and how to do change-point detection.

Difficulty level: Beginner
Duration: 2:49
Speaker: : MATLAB®

This tutorial walks through several common methods for visualizing your data in different ways depending on your data type.

Difficulty level: Beginner
Duration: 6:10
Speaker: : MATLAB®

This tutorial illustrates several ways to approach predictive modeling and machine learning with MATLAB.

Difficulty level: Beginner
Duration: 6:27
Speaker: : MATLAB®

This brief tutorial goes over how you can easily work with big data as you would with any size of data.

Difficulty level: Beginner
Duration: 3:55
Speaker: : MATLAB®

In this tutorial, you will learn how to deploy your models outside of your local MATLAB environment, enabling wider sharing and collaboration.

Difficulty level: Beginner
Duration: 3:52
Speaker: : MATLAB®

This tutorial provides instruction on how to simulate brain tumors with TVB (reproducing publication: Marinazzo et al. 2020 Neuroimage). This tutorial comprises a didactic video, jupyter notebooks, and full data set for the construction of virtual brains from patients and health controls.

Difficulty level: Intermediate
Duration: 10:01