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This lesson gives an introduction to high-performance computing with the Compute Canada network, first providing an overview of use cases for HPC and then a hands-on tutorial. Though some examples might seem specific to the Calcul Québec, all computing clusters in the Compute Canada network share the same software modules and environments.

Difficulty level: Beginner
Duration: 02:49:34

This talk presents an overview of CBRAIN, a web-based platform that allows neuroscientists to perform computationally intensive data analyses by connecting them to high-performance computing facilities across Canada and around the world.

Difficulty level: Beginner
Duration: 56:07
Speaker: : Shawn Brown

This lecture provides an introduction to entropy in general, and multi-scale entropy (MSE) in particular, highlighting the potential clinical applications of the latter. 

Difficulty level: Intermediate
Duration: 39:05
Speaker: : Jil Meier

This lecture covers the rationale for developing the DAQCORD, a framework for the design, documentation, and reporting of data curation methods in order to advance the scientific rigour, reproducibility, and analysis of data.

Difficulty level: Intermediate
Duration: 17:08
Speaker: : Ari Ercole

This tutorial demonstrates how to work with neuronal data using MATLAB, including actional potentials and spike counts, orientation tuing curves in visual cortex, and spatial maps of firing rates.

Difficulty level: Intermediate
Duration: 5:17
Speaker: : Mike X. Cohen

In this lesson, users will learn how to appropriately sort and bin neural spikes, allowing for the generation of a common and powerful visualization tool in neuroscience, the histogram. 

Difficulty level: Intermediate
Duration: 5:31
Speaker: : Mike X. Cohen

Followers of this lesson will learn how to compute, visualize and quantify the tuning curves of individual neurons. 

Difficulty level: Intermediate
Duration: 13:48
Speaker: : Mike X. Cohen

This lesson demonstrates how to programmatically generate a spatial map of neuronal spike counts using MATLAB.

Difficulty level: Intermediate
Duration: 12:16
Speaker: : Mike X. Cohen

In this lesson, users are shown how to create a spatial map of neuronal orientation tuning. 

Difficulty level: Intermediate
Duration: 13:11
Speaker: : Mike X. Cohen

This video will document how to run a correlation analysis between the gray matter volume of two different structures using the output from brainlife app-freesurfer-stats.

Difficulty level: Beginner
Duration: 1:33
Speaker: :

This lesson introduces some practical exercises which accompany the Synapses and Networks portion of this Neuroscience for Machine Learners course. 

Difficulty level: Intermediate
Duration: 3:51
Speaker: : Dan Goodman

This module explores sensation in the brain: what organs are involved, sensory pathways, processing centers, and theories of integration.

Difficulty level: Beginner
Duration: 7:17
Speaker: : Colin Fausnaught

This module covers how the brain interacts with the world through motor movements. Motor movements underlie so much of our functioning, our speech, the opening and closing of our eyes, and the beating of our hearts.

Difficulty level: Beginner
Duration: 5:00
Speaker: : Harrison Canning

This lesson provides an overview of the structure and function of the neuron, its components and mechanisms, action potentials, and the many glial cells that support it.

Difficulty level: Beginner
Duration: 8:31
Speaker: : Colin Fausnaught

This module explains how neurons come together to create the networks that give rise to our thoughts. The totality of our neurons and their connection is called our connectome. Learn how this connectome changes as we learn, and computes information.

Difficulty level: Beginner
Duration: 7:13
Speaker: : Harrison Canning

This lesson continues with the second workshop on reproducible science, focusing on additional open source tools for researchers and data scientists, such as the R programming language for data science, as well as associated tools like RStudio and R Markdown. Additionally, users are introduced to Python and iPython notebooks, Google Colab, and are given hands-on tutorials on how to create a Binder environment, as well as various containers in Docker and Singularity.

Difficulty level: Beginner
Duration: 1:16:04

This lesson contains both a lecture and a tutorial component. The lecture (0:00-20:03 of YouTube video) discusses both the need for intersectional approaches in healthcare as well as the impact of neglecting intersectionality in patient populations. The lecture is followed by a practical tutorial in both Python and R on how to assess intersectional bias in datasets. Links to relevant code and data are found below. 

Difficulty level: Beginner
Duration: 52:26

This is a hands-on tutorial on PLINK, the open source whole genome association analysis toolset. The aims of this tutorial are to teach users how to perform basic quality control on genetic datasets, as well as to identify and understand GWAS summary statistics. 

Difficulty level: Intermediate
Duration: 1:27:18
Speaker: : Dan Felsky

This is a tutorial on using the open-source software PRSice to calculate a set of polygenic risk scores (PRS) for a study sample. Users will also learn how to read PRS into R, visualize distributions, and perform basic association analyses. 

Difficulty level: Intermediate
Duration: 1:53:34
Speaker: : Dan Felsky

This is a tutorial introducing participants to the basics of RNA-sequencing data and how to analyze its features using Seurat. 

Difficulty level: Intermediate
Duration: 1:19:17
Speaker: : Sonny Chen