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The simulation of the virtual epileptic patient is presented as an example of advanced brain simulation as a translational approach to deliver improved results in clinics. The fundamentals of epilepsy are explained. On this basis, the concept of epilepsy simulation is developed. By using an iPython notebook, the detailed process of this approach is explained step by step. In the end, you are able to perform simple epilepsy simulations your own.

Difficulty level: Beginner
Duration: 1:28:53
Speaker: : Julie Courtiol

Explore how to setup an epileptic seizure simulation with the TVB graphical user interface. This lesson will show you how to program the epileptor model in the brain network to simulate a epileptic seizure originating in the hippocampus. It will also show how to upload and view mouse connectivity data, as well as give a short introduction to the python script interface of TVB.

Difficulty level: Intermediate
Duration: 58:06
Speaker: : Paul Triebkorn

Learn how to simulate seizure events and epilepsy in The Virtual Brain. We will look at the paper: On the Nature of Seizure Dynamics which describes a new local model called the Epileptor, and apply this same model in The Virtual Brain. This is part 1 of 2 in a series explaining how to use the Epileptor. In this part, we focus on setting up the parameters.

Difficulty level: Beginner
Duration: 4:44
Speaker: : Paul Triebkorn

Manipulate the default connectome provided with TVB to see how structural lesions effect brain dynamics. In this hands-on session you will insert lesions into the connectome within the TVB graphical user interface. Afterwards the modified connectome will be used for simulations and the resulting activity will be analysed using functional connectivity.

Difficulty level: Beginner
Duration: 31:22
Speaker: : Paul Triebkorn

Brief introduction to Research Resource Identifiers (RRIDs), persistent and unique identifiers for referencing a research resource. 

Difficulty level: Beginner
Duration: 1:30
Speaker: : Anita Bandrowski

Research Resource Identifiers (RRIDs) are ID numbers assigned to help researchers cite key resources (antibodies, model organisms and software projects) in the biomedical literature to improve transparency of research methods.

Difficulty level: Beginner
Duration: 1:01:36
Speaker: : Maryann Martone

Computational models provide a framework for integrating data across spatial scales and for exploring hypotheses about the biological mechanisms underlying neuronal and network dynamics. However, as models increase in complexity, additional barriers emerge to the creation, exchange, and re-use of models. Successful projects have created standards for describing complex models in neuroscience and provide open source tools to address these issues. This lecture provides an overview of these projects and make a case for expanded use of resources in support of reproducibility and validation of models against experimental data.

Difficulty level: Beginner
Duration: 1:00:39
Speaker: : Sharon Crook

Introduction to the Brain Imaging Data Structure (BIDS): a standard for organizing human neuroimaging datasets. This lecture was part of the 2018 Neurohackademy, a 2-week hands-on summer institute in neuroimaging and data science held at the University of Washington eScience Institute.

Difficulty level: Intermediate
Duration: 56:49

NWB: An ecosystem for neurophysiology data standardization

Difficulty level: Beginner
Duration: 29:53
Speaker: : Oliver Ruebel

NWB: An ecosystem for neurophysiology data standardization

Difficulty level: Intermediate
Duration: 29:53
Speaker: : Oliver Ruebel

Learn how to create a standard extracellular electrophysiology dataset in NWB using Python

Difficulty level: Intermediate
Duration: 45:46
Speaker: : Ryan Ly

Learn how to create a standard calcium imaging dataset in NWB using Python

Difficulty level: Intermediate
Duration: 31:04
Speaker: : Ryan Ly

Learn how to create a standard intracellular electrophysiology dataset in NWB

Difficulty level: Intermediate
Duration: 20:23
Speaker: : Pamela Baker

Learn how to use the icephys-metadata extension to enter meta-data detailing your experimental paradigm

Difficulty level: Intermediate
Duration: 27:18
Speaker: : Oliver Ruebel

Learn how to build and share extensions in NWB

Difficulty level: Advanced
Duration: 20:29
Speaker: : Ryan Ly

Learn how to build custom APIs for extension

Difficulty level: Advanced
Duration: 25:40
Speaker: : Andrew Tritt

Learn how to handle writing very large data in PyNWB

Difficulty level: Advanced
Duration: 26:50
Speaker: : Andrew Tritt

Learn how to create a standard extracellular electrophysiology dataset in NWB using MATLAB

Difficulty level: Intermediate
Duration: 45:46
Speaker: : Ben Dichter

Learn how to create a standard calcium imaging dataset in NWB using MATLAB

Difficulty level: Intermediate
Duration: 39:10
Speaker: : Ben Dichter

Learn how to create a standard intracellular electrophysiology dataset in NWB

Difficulty level: Intermediate
Duration: 20:22
Speaker: : Pamela Baker