Skip to main content

This lesson is a general overview of overarching concepts in neuroinformatics research, with a particular focus on clinical approaches to defining, measuring, studying, diagnosing, and treating various brain disorders. Also described are the complex, multi-level nature of brain disorders and the data associated with them, from genes and individual cells up to cortical microcircuits and whole-brain network dynamics. Given the heterogeneity of brain disorders and their underlying mechanisms, this lesson lays out a case for multiscale neuroscience data integration.

Difficulty level: Intermediate
Duration: 1:09:33
Speaker: : Sean Hill

In this tutorial on simulating whole-brain activity using Python, participants can follow along using corresponding code and repositories, learning the basics of neural oscillatory dynamics, evoked responses and EEG signals, ultimately leading to the design of a network model of whole-brain anatomical connectivity. 

Difficulty level: Intermediate
Duration: 1:16:10
Speaker: : John Griffiths

This lesson breaks down the principles of Bayesian inference and how it relates to cognitive processes and functions like learning and perception. It is then explained how cognitive models can be built using Bayesian statistics in order to investigate how our brains interface with their environment. 

This lesson corresponds to slides 1-64 in the PDF below. 

Difficulty level: Intermediate
Duration: 1:28:14

This lecture and tutorial focuses on measuring human functional brain networks, as well as how to account for inherent variability within those networks. 

Difficulty level: Intermediate
Duration: 50:44
Speaker: : Caterina Gratton

This lecture presents an overview of functional brain parcellations, as well as a set of tutorials on bootstrap agregation of stable clusters (BASC) for fMRI brain parcellation.

Difficulty level: Advanced
Duration: 50:28
Speaker: : Pierre Bellec
Course:

Neuronify is an educational tool meant to create intuition for how neurons and neural networks behave. You can use it to combine neurons with different connections, just like the ones we have in our brain, and explore how changes on single cells lead to behavioral changes in important networks. Neuronify is based on an integrate-and-fire model of neurons. This is one of the simplest models of neurons that exist. It focuses on the spike timing of a neuron and ignores the details of the action potential dynamics. These neurons are modeled as simple RC circuits. When the membrane potential is above a certain threshold, a spike is generated and the voltage is reset to its resting potential. This spike then signals other neurons through its synapses.

Neuronify aims to provide a low entry point to simulation-based neuroscience.

Difficulty level: Beginner
Duration: 01:25
Speaker: : Neuronify

This tutorial demonstrates how to work with neuronal data using MATLAB, including actional potentials and spike counts, orientation tuing curves in visual cortex, and spatial maps of firing rates.

Difficulty level: Intermediate
Duration: 5:17
Speaker: : Mike X. Cohen

This lesson instructs users on how to import electrophysiological neural data into MATLAB, as well as how to convert spikes to a data matrix.

Difficulty level: Intermediate
Duration: 11:37
Speaker: : Mike X. Cohen

In this lesson, users will learn how to appropriately sort and bin neural spikes, allowing for the generation of a common and powerful visualization tool in neuroscience, the histogram. 

Difficulty level: Intermediate
Duration: 5:31
Speaker: : Mike X. Cohen

Followers of this lesson will learn how to compute, visualize and quantify the tuning curves of individual neurons. 

Difficulty level: Intermediate
Duration: 13:48
Speaker: : Mike X. Cohen

This lesson demonstrates how to programmatically generate a spatial map of neuronal spike counts using MATLAB.

Difficulty level: Intermediate
Duration: 12:16
Speaker: : Mike X. Cohen

In this lesson, users will learn about human brain signals as measured by electroencephalography (EEG), as well as associated neural signatures such as steady state visually evoked potentials (SSVEPs) and alpha oscillations. 

Difficulty level: Intermediate
Duration: 8:51
Speaker: : Mike X. Cohen

This lecture describes the principles of EEG electrode placement in both 2- and 3-dimensional formats. 

Difficulty level: Intermediate
Duration: 12:16
Speaker: : Mike X. Cohen

This tutorial walks users through performing Fourier Transform (FFT) spectral analysis of a single EEG channel using MATLAB. 

Difficulty level: Intermediate
Duration: 13:39
Speaker: : Mike X. Cohen

This tutorial builds on the previous lesson's demonstration of spectral analysis of one EEG channel. Here, users will learn how to compute and visualize spectral power from all EEG channels using MATLAB. 

Difficulty level: Intermediate
Duration: 12:34
Speaker: : Mike X. Cohen

In this lesson, users will learn more about the steady-state visually evoked potential (SSEVP), as well as how to create and interpret topographical maps derived from such studies. 

Difficulty level: Intermediate
Duration: 9:10
Speaker: : Mike X. Cohen

This lesson teaches users how to extract edogenous brain waves from EEG data, specifically oscillations constrained to the 8-12 Hz frequency band, conventionally named alpha. 

Difficulty level: Intermediate
Duration: 13:23
Speaker: : Mike X. Cohen

In the final lesson of this module, users will learn how to correlate endogenous alpha power with SSVEP amplitude from EEG data using MATLAB.

Difficulty level: Intermediate
Duration: 12:36
Speaker: : Mike X. Cohen

This lesson provides an introduction to biologically detailed computational modelling of neural dynamics, including neuron membrane potential simulation and F-I curves. 

Difficulty level: Intermediate
Duration: 8:21
Speaker: : Mike X. Cohen

This lesson introduces users to MATLAB live scripts; interactive documents that combine MATLAB code with formatted text, equations, and images in a single environment. 

Difficulty level: Intermediate
Duration: 13:11
Speaker: : Mike X. Cohen