This lesson is a general overview of overarching concepts in neuroinformatics research, with a particular focus on clinical approaches to defining, measuring, studying, diagnosing, and treating various brain disorders. Also described are the complex, multi-level nature of brain disorders and the data associated with them, from genes and individual cells up to cortical microcircuits and whole-brain network dynamics. Given the heterogeneity of brain disorders and their underlying mechanisms, this lesson lays out a case for multiscale neuroscience data integration.

In this tutorial on simulating whole-brain activity using Python, participants can follow along using corresponding code and repositories, learning the basics of neural oscillatory dynamics, evoked responses and EEG signals, ultimately leading to the design of a network model of whole-brain anatomical connectivity. 

This lesson breaks down the principles of Bayesian inference and how it relates to cognitive processes and functions like learning and perception. It is then explained how cognitive models can be built using Bayesian statistics in order to investigate how our brains interface with their environment. 

This lesson corresponds to slides 1-64 in the PDF below. 

Whereas the previous two lessons described the biophysical and signalling properties of individual neurons, this lesson describes properties of those units when part of larger networks. 

This lesson goes over some examples of how machine learners and computational neuroscientists go about designing and building neural network models inspired by biological brain systems. 

This lecture and tutorial focuses on measuring human functional brain networks, as well as how to account for inherent variability within those networks. 

This lecture presents an overview of functional brain parcellations, as well as a set of tutorials on bootstrap agregation of stable clusters (BASC) for fMRI brain parcellation.

Neuronify is an educational tool meant to create intuition for how neurons and neural networks behave. You can use it to combine neurons with different connections, just like the ones we have in our brain, and explore how changes on single cells lead to behavioral changes in important networks. Neuronify is based on an integrate-and-fire model of neurons. This is one of the simplest models of neurons that exist. It focuses on the spike timing of a neuron and ignores the details of the action potential dynamics. These neurons are modeled as simple RC circuits. When the membrane potential is above a certain threshold, a spike is generated and the voltage is reset to its resting potential. This spike then signals other neurons through its synapses.

Neuronify aims to provide a low entry point to simulation-based neuroscience.

This lesson provides an introduction to biologically detailed computational modelling of neural dynamics, including neuron membrane potential simulation and F-I curves. 

In this lesson, users learn how to use MATLAB to build an adaptive exponential integrate and fire (AdEx) neuron model. 

In this lesson, users learn about the practical differences between MATLAB scripts and functions, as well as how to embed their neuronal simulation into a callable function.  

This lesson teaches users how to generate a frequency-current (F-I) curve, which describes the function that relates the net synaptic current (I) flowing into a neuron to its firing rate (F). 

This lecture covers a lot of post-war developments in the science of the mind, focusing first on the cognitive revolution, and concluding with living machines.

This lesson delves into the the structure of one of the brain's most elemental computational units, the neuron, and how said structure influences computational neural network models. 

In this lesson you will learn how machine learners and neuroscientists construct abstract computational models based on various neurophysiological signalling properties. 

This lesson contains practical exercises which accompanies the first few lessons of the Neuroscience for Machine Learners (Neuro4ML) course. 

This lesson introduces some practical exercises which accompany the Synapses and Networks portion of this Neuroscience for Machine Learners course. 

This lesson describes spike timing-dependent plasticity (STDP), a biological process that adjusts the strength of connections between neurons in the brain, and how one can implement or mimic this process in a computational model. You will also find links for practical exercises at the bottom of this page. 

 In this lesson, you will learn about some of the many methods to train spiking neural networks (SNNs) with either no attempt to use gradients, or only use gradients in a limited or constrained way. 

In this lesson, you will learn how to train spiking neural networks (SNNs) with a surrogate gradient method.