Manipulate the default connectome provided with TVB to see how structural lesions effect brain dynamics. In this hands-on session you will insert lesions into the connectome within the TVB graphical user interface (GUI). Afterwards, the modified connectome will be used for simulations and the resulting activity will be analysed using functional connectivity.
This lesson describes the principles underlying functional magnetic resonance imaging (fMRI), diffusion-weighted imaging (DWI), tractography, and parcellation. These tools and concepts are explained in a broader context of neural connectivity and mental health.
This tutorial introduces pipelines and methods to compute brain connectomes from fMRI data. With corresponding code and repositories, participants can follow along and learn how to programmatically preprocess, curate, and analyze functional and structural brain data to produce connectivity matrices.
This lesson introduces the practical exercises which accompany the previous lessons on animal and human connectomes in the brain and nervous system.
This lecture and tutorial focuses on measuring human functional brain networks, as well as how to account for inherent variability within those networks.
This lecture presents an overview of functional brain parcellations, as well as a set of tutorials on bootstrap agregation of stable clusters (BASC) for fMRI brain parcellation.
This lecture covers FAIR atlases, including their background and construction, as well as how they can be created in line with the FAIR principles.
This lesson is a general overview of overarching concepts in neuroinformatics research, with a particular focus on clinical approaches to defining, measuring, studying, diagnosing, and treating various brain disorders. Also described are the complex, multi-level nature of brain disorders and the data associated with them, from genes and individual cells up to cortical microcircuits and whole-brain network dynamics. Given the heterogeneity of brain disorders and their underlying mechanisms, this lesson lays out a case for multiscale neuroscience data integration.
This lesson gives an in-depth introduction of ethics in the field of artificial intelligence, particularly in the context of its impact on humans and public interest. As the healthcare sector becomes increasingly affected by the implementation of ever stronger AI algorithms, this lecture covers key interests which must be protected going forward, including privacy, consent, human autonomy, inclusiveness, and equity.
This is a continuation of the talk on the cellular mechanisms of neuronal communication, this time at the level of brain microcircuits and associated global signals like those measureable by electroencephalography (EEG). This lecture also discusses EEG biomarkers in mental health disorders, and how those cortical signatures may be simulated digitally.
This lecture picks up from the previous lesson, providing an overview of neuroimaging techniques and their clinical applications.
This lesson provides a basic introduction to clinical presentation of schizophrenia, its etiology, and current treatment options.
This lecture focuses on the rationale for employing neuroimaging methods for movement disorders.
This lecture provides an introduction to entropy in general, and multi-scale entropy (MSE) in particular, highlighting the potential clinical applications of the latter.
This lecture covers the rationale for developing the DAQCORD, a framework for the design, documentation, and reporting of data curation methods in order to advance the scientific rigour, reproducibility, and analysis of data.
The state of the field regarding the diagnosis and treatment of major depressive disorder (MDD) is discussed. Current challenges and opportunities facing the research and clinical communities are outlined, including appropriate quantitative and qualitative analyses of the heterogeneity of biological, social, and psychiatric factors which may contribute to MDD.
This lesson delves into the opportunities and challenges of telepsychiatry. While novel digital approaches to clinical research and care have the potential to improve and accelerate patient outcomes, researchers and care providers must consider new population factors, such as digital disparity.
This lecture covers visualizing extracellular neurotransmitter dynamics
This lesson goes over the basic mechanisms of neural synapses, the space between neurons where signals may be transmitted.
This lesson describes spike timing-dependent plasticity (STDP), a biological process that adjusts the strength of connections between neurons in the brain, and how one can implement or mimic this process in a computational model. You will also find links for practical exercises at the bottom of this page.