This lesson provides an introduction to biologically detailed computational modelling of neural dynamics, including neuron membrane potential simulation and F-I curves. 

In this lesson, users learn how to use MATLAB to build an adaptive exponential integrate and fire (AdEx) neuron model. 

In this lesson, users learn about the practical differences between MATLAB scripts and functions, as well as how to embed their neuronal simulation into a callable function.  

This lesson teaches users how to generate a frequency-current (F-I) curve, which describes the function that relates the net synaptic current (I) flowing into a neuron to its firing rate (F). 

This lecture provides an introduction to the application of genetic testing in neurodevelopmental disorders.

This is the first of two workshops on reproducibility in science, during which participants are introduced to concepts of FAIR and open science. After discussing the definition of and need for FAIR science, participants are walked through tutorials on installing and using Github and Docker, the powerful, open-source tools for versioning and publishing code and software, respectively.

This lesson describes the fundamentals of genomics, from central dogma to design and implementation of GWAS, to the computation, analysis, and interpretation of polygenic risk scores. 

This is a hands-on tutorial on PLINK, the open source whole genome association analysis toolset. The aims of this tutorial are to teach users how to perform basic quality control on genetic datasets, as well as to identify and understand GWAS summary statistics. 

This is a tutorial on using the open-source software PRSice to calculate a set of polygenic risk scores (PRS) for a study sample. Users will also learn how to read PRS into R, visualize distributions, and perform basic association analyses. 

This lesson contains the slides (pptx) of a lecture discussing the necessary concepts and tools for taking into account population stratification and admixture in the context of genome-wide association studies (GWAS). The free-access software Tractor and its advantages in GWAS are also discussed. 

This lesson is an overview of transcriptomics, from fundamental concepts of the central dogma and RNA sequencing at the single-cell level, to how genetic expression underlies diversity in cell phenotypes. 

This is a tutorial introducing participants to the basics of RNA-sequencing data and how to analyze its features using Seurat. 

This tutorial demonstrates how to perform cell-type deconvolution in order to estimate how proportions of cell-types in the brain change in response to various conditions. While these techniques may be useful in addressing a wide range of scientific questions, this tutorial will focus on the cellular changes associated with major depression (MDD). 

Similarity Network Fusion (SNF) is a computational method for data integration across various kinds of measurements, aimed at taking advantage of the common as well as complementary information in different data types. This workshop walks participants through running SNF on EEG and genomic data using RStudio.

This lecture covers a lot of post-war developments in the science of the mind, focusing first on the cognitive revolution, and concluding with living machines.

This lesson introduces several open science tools like Docker and Apptainer which can be used to develop portable and reproducible software environments. 

This lecture covers a wide range of aspects regarding neuroinformatics and data governance, describing both their historical developments and current trajectories. Particular tools, platforms, and standards to make your research more FAIR are also discussed.

Introduction of the Foundations of Machine Learning in Python course - Day 01.

High-Performance Computing and Analytics Lab, University of Bonn

Optimization for machine learning - Day 02 lecture of the Foundations of Machine Learning in Python course.

High-Performance Computing and Analytics Lab, University of Bonn

Linear Algebra for Machine Learning - Day 03 lecture of the Foundations of Machine Learning in Python course.

High-Performance Computing and Analytics Lab, University of Bonn