FAIR principles and methods currently in development for assessing FAIRness.

Tutorial describing the basic search and navigation features of the Allen Mouse Brain Atlas

Tutorial describing the basic search and navigation features of the Allen Developing Mouse Brain Atlas

This tutorial demonstrates how to use the differential search feature of the Allen Mouse Brain Atlas to find gene markers for different regions of the brain and to visualize this gene expression in three-dimensional space. Differential search is also available for the Allen Developing Mouse Brain Atlas and the Allen Human Brain Atlas.

The Mouse Phenome Database (MPD) provides access to primary experimental trait data, genotypic variation, protocols and analysis tools for mouse genetic studies. Data are contributed by investigators worldwide and represent a broad scope of phenotyping endpoints and disease-related traits in naïve mice and those exposed to drugs, environmental agents or other treatments. MPD ensures rigorous curation of phenotype data and supporting documentation using relevant ontologies and controlled vocabularies. As a repository of curated and integrated data, MPD provides a means to access/re-use baseline data, as well as allows users to identify sensitized backgrounds for making new mouse models with genome editing technologies, analyze trait co-inheritance, benchmark assays in their own laboratories, and many other research applications. MPD’s primary source of funding is NIDA. For this reason, a majority of MPD data is neuro- and behavior-related.

GeneWeaver is a web application for the integrated cross-species analysis of functional genomics data to find convergent evidence from heterogeneous sources. The application consists of a large database of gene sets curated from multiple public data resources and curated submissions, along with a suite of analysis tools designed to allow flexible, customized workflows through web-based interactive analysis or scripted API driven analysis. Gene sets come from multiple widely studied species and include ontology annotations, brain gene expression atlases, systems genetic study results, gene regulatory information, pathway databases, drug interaction databases and many other sources. Users can retrieve, store, analyze and share gene sets through a graded access system. Analysis tools are based on combinatorics and statistical methods for comparing, contrasting and classifying gene sets based on their members.

In this lesson, users will learn about human brain signals as measured by electroencephalography (EEG), as well as associated neural signatures such as steady state visually evoked potentials (SSVEPs) and alpha oscillations. 

This lecture describes the principles of EEG electrode placement in both 2- and 3-dimensional formats. 

This tutorial walks users through performing Fourier Transform (FFT) spectral analysis of a single EEG channel using MATLAB. 

This tutorial builds on the previous lesson's demonstration of spectral analysis of one EEG channel. Here, users will learn how to compute and visualize spectral power from all EEG channels using MATLAB. 

In this lesson, users will learn more about the steady-state visually evoked potential (SSEVP), as well as how to create and interpret topographical maps derived from such studies. 

This lesson teaches users how to extract edogenous brain waves from EEG data, specifically oscillations constrained to the 8-12 Hz frequency band, conventionally named alpha. 

In the final lesson of this module, users will learn how to correlate endogenous alpha power with SSVEP amplitude from EEG data using MATLAB.

This is a continuation of the talk on the cellular mechanisms of neuronal communication, this time at the level of brain microcircuits and associated global signals like those measureable by electroencephalography (EEG). This lecture also discusses EEG biomarkers in mental health disorders, and how those cortical signatures may be simulated digitally.

This is an in-depth guide on EEG signals and their interaction within brain microcircuits. Participants are also shown techniques and software for simulating, analyzing, and visualizing these signals.

In this tutorial on simulating whole-brain activity using Python, participants can follow along using corresponding code and repositories, learning the basics of neural oscillatory dynamics, evoked responses and EEG signals, ultimately leading to the design of a network model of whole-brain anatomical connectivity. 

The tutorial is intended primarily for beginners, but it will also beneficial to experimentalists who understand electroencephalography and event related techniques, but need additional knowledge in annotation, standardization, long-term storage and publication of data.

Introduction to the first phases of EEG/ERP data lifecycle