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This lesson is a general overview of overarching concepts in neuroinformatics research, with a particular focus on clinical approaches to defining, measuring, studying, diagnosing, and treating various brain disorders. Also described are the complex, multi-level nature of brain disorders and the data associated with them, from genes and individual cells up to cortical microcircuits and whole-brain network dynamics. Given the heterogeneity of brain disorders and their underlying mechanisms, this lesson lays out a case for multiscale neuroscience data integration.

Difficulty level: Intermediate
Duration: 1:09:33
Speaker: : Sean Hill

In this tutorial on simulating whole-brain activity using Python, participants can follow along using corresponding code and repositories, learning the basics of neural oscillatory dynamics, evoked responses and EEG signals, ultimately leading to the design of a network model of whole-brain anatomical connectivity. 

Difficulty level: Intermediate
Duration: 1:16:10
Speaker: : John Griffiths

This lesson breaks down the principles of Bayesian inference and how it relates to cognitive processes and functions like learning and perception. It is then explained how cognitive models can be built using Bayesian statistics in order to investigate how our brains interface with their environment. 

This lesson corresponds to slides 1-64 in the PDF below. 

Difficulty level: Intermediate
Duration: 1:28:14

This talk gives a brief overview of current efforts to collect and share the Brain Reference Architecture (BRA) data involved in the construction of a whole-brain architecture that assigns functions to major brain organs. 

Difficulty level: Beginner
Duration: 4:02

This brief talk discusses the idea that music, as a naturalistic stimulus, offers a window into higher cognition and various levels of neural architecture.    

Difficulty level: Beginner
Duration: 4:04
Speaker: : Sarah Faber

In this short talk you will learn about The Neural System Laboratory, which aims to develop and implement new technologies for analysis of brain architecture, connectivity, and brain-wide gene and molecular level organization.

Difficulty level: Beginner
Duration: 8:38
Speaker: : Trygve Leergard

Whereas the previous two lessons described the biophysical and signalling properties of individual neurons, this lesson describes properties of those units when part of larger networks. 

Difficulty level: Intermediate
Duration: 6:00
Speaker: : Marcus Ghosh

This lesson goes over some examples of how machine learners and computational neuroscientists go about designing and building neural network models inspired by biological brain systems. 

Difficulty level: Intermediate
Duration: 12:52
Speaker: : Dan Goodman

This lecture and tutorial focuses on measuring human functional brain networks, as well as how to account for inherent variability within those networks. 

Difficulty level: Intermediate
Duration: 50:44
Speaker: : Caterina Gratton

This lecture presents an overview of functional brain parcellations, as well as a set of tutorials on bootstrap agregation of stable clusters (BASC) for fMRI brain parcellation.

Difficulty level: Advanced
Duration: 50:28
Speaker: : Pierre Bellec
Course:

Neuronify is an educational tool meant to create intuition for how neurons and neural networks behave. You can use it to combine neurons with different connections, just like the ones we have in our brain, and explore how changes on single cells lead to behavioral changes in important networks. Neuronify is based on an integrate-and-fire model of neurons. This is one of the simplest models of neurons that exist. It focuses on the spike timing of a neuron and ignores the details of the action potential dynamics. These neurons are modeled as simple RC circuits. When the membrane potential is above a certain threshold, a spike is generated and the voltage is reset to its resting potential. This spike then signals other neurons through its synapses.

Neuronify aims to provide a low entry point to simulation-based neuroscience.

Difficulty level: Beginner
Duration: 01:25
Speaker: : Neuronify

This talk gives an overview of the Human Brain Project, a 10-year endeavour putting in place a cutting-edge research infrastructure that will allow scientific and industrial researchers to advance our knowledge in the fields of neuroscience, computing, and brain-related medicine.

Difficulty level: Intermediate
Duration: 24:52
Speaker: : Katrin Amunts

This lecture gives an introduction to the European Academy of Neurology, its recent achievements and ambitions.

Difficulty level: Intermediate
Duration: 21:57
Speaker: : Paul Boon

This talk enumerates the challenges regarding data accessibility and reusability inherent in the current scientific publication system, and discusses novel approaches to these challenges, such as the EBRAINS Live Papers platform. 

Difficulty level: Beginner
Duration: 18:08
Speaker: : Andrew Davison

This lesson aims to define computational neuroscience in general terms, while providing specific examples of highly successful computational neuroscience projects. 

Difficulty level: Beginner
Duration: 59:21
Speaker: : Alla Borisyuk

This lesson covers membrane potential of neurons, and how parameters around this potential have direct consequences on cellular communication at both the individual and population level. 

Difficulty level: Beginner
Duration: 28:08
Speaker: : Carl Petersen

In this lesson you will learn about neurons' ability to generate signals called action potentials, and biophysics of voltage-gated ion channels.

Difficulty level: Beginner
Duration: 27:47
Speaker: : Carl Petersen

This lesson discusses voltage-gating kinetics of sodium and potassium channels.

Difficulty level: Beginner
Duration: 19:20
Speaker: : Carl Petersen

In this lesson, you will learn about the ionic basis of the action potential, including the Hodgkin-Huxley model.

Difficulty level: Beginner
Duration: 28:29
Speaker: : Carl Petersen

This lesson delves into the specifics of how action potentials propagate through individual neurons.

Difficulty level: Beginner
Duration: 23:16
Speaker: : Carl Petersen