This talk describes the NIH-funded SPARC Data Structure, and how this project navigates ontology development while keeping in mind the FAIR science principles.
This lesson provides an overview of the current status in the field of neuroscientific ontologies, presenting examples of data organization and standards, particularly from neuroimaging and electrophysiology.
This lesson continues from part one of the lecture Ontologies, Databases, and Standards, diving deeper into a description of ontologies and knowledg graphs.
This lecture covers structured data, databases, federating neuroscience-relevant databases, and ontologies.
This lecture covers FAIR atlases, including their background and construction, as well as how they can be created in line with the FAIR principles.
This lecture focuses on ontologies for clinical neurosciences.
This lecture provides an introduction to optogenetics, a biological technique to control the activity of neurons or other cell types with light.
This primer on optogenetics primer discusses how to manipulate neuronal populations with light at millisecond resolution and offers possible applications such as curing the blind and "playing the piano" with cortical neurons.
This lecture gives an introduction to the types of glial cells, homeostasis (influence of cerebral blood flow and influence on neurons), insulation and protection of axons (myelin sheath; nodes of Ranvier), microglia and reactions of the CNS to injury.
This lecture focuses on how the immune system can target and attack the nervous system to produce autoimmune responses that may result in diseases such as multiple sclerosis, neuromyelitis, and lupus cerebritis manifested by motor, sensory, and cognitive impairments. Despite the fact that the brain is an immune-privileged site, autoreactive lymphocytes producing proinflammatory cytokines can cause active brain inflammation, leading to myelin and axonal loss.
This lecture provides an overview of some of the essential concepts in neuropharmacology (e.g. receptor binding, agonism, antagonism), an introduction to pharmacodynamics and pharmacokinetics, and an overview of the drug discovery process relative to diseases of the central nervous system.
This lecture covers the ethical implications of the use of pharmaceuticals to enhance brain functions and was part of the Neuro Day Workshop held by the NeuroSchool of Aix Marseille University.
While the previous lesson in the Neuro4ML course dealt with the mechanisms involved in individual synapses, this lesson discusses how synapses and their neurons' firing patterns may change over time.
In this lesson, you will learn about how machine learners and computational neuroscientists design and build models of neuronal synapses.
How does the brain learn? This lecture discusses the roles of development and adult plasticity in shaping functional connectivity.
This lesson goes into the mechanisms behind changes in synaptic function created by learning.