The simulation of the virtual epileptic patient is presented as an example of advanced brain simulation as a translational approach to deliver improved results in clinics. The fundamentals of epilepsy are explained. On this basis, the concept of epilepsy simulation is developed. By using an iPython notebook, the detailed process of this approach is explained step by step. In the end, you are able to perform simple epilepsy simulations your own.

Explore how to setup an epileptic seizure simulation with the TVB graphical user interface. This lesson will show you how to program the epileptor model in the brain network to simulate a epileptic seizure originating in the hippocampus. It will also show how to upload and view mouse connectivity data, as well as give a short introduction to the python script interface of TVB.

Learn how to simulate seizure events and epilepsy in The Virtual Brain. We will look at the paper: On the Nature of Seizure Dynamics which describes a new local model called the Epileptor, and apply this same model in The Virtual Brain. This is part 1 of 2 in a series explaining how to use the Epileptor. In this part, we focus on setting up the parameters.

Introduction to the Mathematics chapter of Datalabcc's "Foundations in Data Science" series.

Primer on elementary algebra

Primer on linear algebra

Primer on systems of linear equations

Primer on calculus

How calculus relates to optimization

Big O notation

Basics of probability.

How does the brain learn? This lecture discusses the roles of development and adult plasticity in shaping functional connectivity.

Introduction to neurons, synaptic transmission, and ion channels.

2nd part of the lecture. Introduction to cell receptors and signalling cascades

Introduction to the types of glial cells, homeostasis (influence of cerebral blood flow and influence on neurons), insulation and protection of axons (myelin sheath; nodes of Ranvier), microglia and reactions of the CNS to injury.

Introduction to the origin and differentiation of myelinating cell types, molecular mechanisms defining onset and progression of myelination, demyelination and remyelination after injury.

This lecture covers: integrating information within a network, modulating and controlling networks, functions and dysfunctions of hippocampal networks, and the integrative network controlling sleep and arousal.

This lecture focuses on the comprehension of nociception and pain sensation. It highlights how the somatosensory system and different molecular partners are involved in nociception and how nociception and pain sensation are studied in rodents and humans and the development of pain therapy.

An overview of some of the essential concepts in neuropharmacology (e.g. receptor binding, agonism, antagonism), an introduction to pharmacodynamics and pharmacokinetics, and an overview of the drug discovery process relative to diseases of the Central Nervous System.

The mechanisms behind changes in synaptic function created by learning.