This primer on optogenetics primer discusses how to manipulate neuronal populations with light at millisecond resolution and offers possible applications such as curing the blind and "playing the piano" with cortical neurons.
2nd part of the lecture. Introduction to cell receptors and signalling cascades
GABAergic interneurons and local inhibition on the circuit level.
The ionic basis of the action potential, including the Hodgkin Huxley model.
Introduction to the course Cellular Mechanisms of Brain Function.
The ionic basis of the action potential, including the Hodgkin Huxley model.
Introduction to the course Cellular Mechanisms of Brain Function.
Ion channels and the movement of ions across the cell membrane.
Spatiotemporal dynamics of the membrane potential.
Action potentials, and biophysics of voltage-gated ion channels.
Voltage-gating kinetics of sodium and potassium channels.
The ionic basis of the action potential, including the Hodgkin Huxley model.
Action potential initiation and propagation.
Neurotransmitter release in the presynaptic specialization.
Synaptic modulation through diffusing neurotransmitters.
Glutamatergic transmission.
Glutamate release after an action potential. Resulting post-synaptic potentials in a biophysically realistic situation.
Glutamatergic excitatory neuronal circuits.
Dendritic spines and their function.
GABAergic inhibition and its receptors.