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This lecture covers computational principles that growth cones employ to detect and respond to environmental chemotactic gradients, focusing particularly on growth-cone shape dynamics.

Difficulty level: Intermediate
Duration: 26:12
Speaker: : Geoff Goodhill

In this lecture you will learn that in developing mouse somatosensory cortex, endogenous Btbd3 translocate to the cell nucleus in response to neuronal activity and oriente primary dendrites toward active axons in the barrel hollow.

Difficulty level: Intermediate
Duration: 27:32
Speaker: : Tomomi Shimogori

In this presentation, the speaker describes some of their recent efforts to characterize the transcriptome of the developing human brain, and and introduction to the BrainSpan project.

Difficulty level: Intermediate
Duration: 30:45
Speaker: : Nenad Sestan

How does the brain learn? This lecture discusses the roles of development and adult plasticity in shaping functional connectivity.

Difficulty level: Beginner
Duration: 1:08:45
Speaker: : Clay Reid

This lecture covers visualizing extracellular neurotransmitter dynamics

Difficulty level: Beginner
Duration: 23:20

This lesson goes over the basic mechanisms of neural synapses, the space between neurons where signals may be transmitted. 

Difficulty level: Intermediate
Duration: 7:03
Speaker: : Marcus Ghosh

This lesson describes spike timing-dependent plasticity (STDP), a biological process that adjusts the strength of connections between neurons in the brain, and how one can implement or mimic this process in a computational model. You will also find links for practical exercises at the bottom of this page. 

Difficulty level: Intermediate
Duration: 12:50
Speaker: : Dan Goodman

This lesson discusses a gripping neuroscientific question: why have neurons developed the discrete action potential, or spike, as a principle method of communication? 

Difficulty level: Intermediate
Duration: 9:34
Speaker: : Dan Goodman

This lecture consists of the second half of the introduction to signal transduction, here focusing on cell receptors and signalling cascades.

Difficulty level: Beginner
Duration: 41:38

In this lesson, you will learn about GABAergic interneurons and local inhibition on the circuit level.

Difficulty level: Beginner
Duration: 16:27
Speaker: : Carl Petersen

This lecture provides an overview of some of the essential concepts in neuropharmacology (e.g. receptor binding, agonism, antagonism), an introduction to pharmacodynamics and pharmacokinetics, and an overview of the drug discovery process relative to diseases of the central nervous system. 

Difficulty level: Beginner
Duration: 45:47

This lecture covers the ethical implications of the use of pharmaceuticals to enhance brain functions and was part of the Neuro Day Workshop held by the NeuroSchool of Aix Marseille University.

Difficulty level: Beginner
Duration: 1:09:29
Speaker: : Eric Racine

While the previous lesson in the Neuro4ML course dealt with the mechanisms involved in individual synapses, this lesson discusses how synapses and their neurons' firing patterns may change over time. 

Difficulty level: Intermediate
Duration: 4:48
Speaker: : Marcus Ghosh

In this lesson, you will learn about how machine learners and computational neuroscientists design and build models of neuronal synapses. 

Difficulty level: Intermediate
Duration: 8:59
Speaker: : Dan Goodman

This lesson goes into the mechanisms behind changes in synaptic function created by learning.

Difficulty level: Beginner
Duration: 27:07
Speaker: : Carl Petersen

This lesson contains both a lecture and a tutorial component. The lecture (0:00-20:03 of YouTube video) discusses both the need for intersectional approaches in healthcare as well as the impact of neglecting intersectionality in patient populations. The lecture is followed by a practical tutorial in both Python and R on how to assess intersectional bias in datasets. Links to relevant code and data are found below. 

Difficulty level: Beginner
Duration: 52:26

This is an introductory lecture on whole-brain modelling, delving into the various spatial scales of neuroscience, neural population models, and whole-brain modelling. Additionally, the clinical applications of building and testing such models are characterized. 

Difficulty level: Intermediate
Duration: 1:24:44
Speaker: : John Griffiths

This is a tutorial on designing a Bayesian inference model to map belief trajectories, with emphasis on gaining familiarity with Hierarchical Gaussian Filters (HGFs).

 

This lesson corresponds to slides 65-90 of the PDF below. 

Difficulty level: Intermediate
Duration: 1:15:04
Speaker: : Daniel Hauke

This lecture discusses what defines an integrative approach regarding research and methods, including various study designs and models which are appropriate choices when attempting to bridge data domains; a necessity when whole-person modelling. 

Difficulty level: Beginner
Duration: 1:28:14
Speaker: : Dan Felsky

Similarity Network Fusion (SNF) is a computational method for data integration across various kinds of measurements, aimed at taking advantage of the common as well as complementary information in different data types. This workshop walks participants through running SNF on EEG and genomic data using RStudio.

Difficulty level: Intermediate
Duration: 1:21:38
Speaker: : Dan Felsky