Brief introduction to Research Resource Identifiers (RRIDs), persistent and unique identifiers for referencing a research resource.
Research Resource Identifiers (RRIDs) are ID numbers assigned to help researchers cite key resources (antibodies, model organisms and software projects) in the biomedical literature to improve transparency of research methods.
The Brain Imaging Data Structure (BIDS) is a standard prescribing a formal way to name and organize MRI data and metadata in a file system that simplifies communication and collaboration between users and enables easier data validation and software development through using consistent paths and naming for data files.
Neurodata Without Borders (NWB) is a data standard for neurophysiology that provides neuroscientists with a common standard to share, archive, use, and build common analysis tools for neurophysiology data.
The Neuroimaging Data Model (NIDM) is a collection of specification documents that define extensions the W3C PROV standard for the domain of human brain mapping. NIDM uses provenance information as means to link components from different stages of the scientific research process from dataset descriptors and computational workflow, to derived data and publication.
Neuroscience Information Exchange (NIX) Format data model allows storing fully annotated scientific datasets, i.e. the data together with rich metadata and their relations in a consistent, comprehensive format. Its aim is to achieve standardization by providing a common data structure and APIs for a multitude of data types and use cases, focused on but not limited to neuroscience. In contrast to most other approaches, the NIX approach is to achieve this flexibility with a minimum set of data model elements.
Computational models provide a framework for integrating data across spatial scales and for exploring hypotheses about the biological mechanisms underlying neuronal and network dynamics. However, as models increase in complexity, additional barriers emerge to the creation, exchange, and re-use of models. Successful projects have created standards for describing complex models in neuroscience and provide open source tools to address these issues. This lecture provides an overview of these projects and make a case for expanded use of resources in support of reproducibility and validation of models against experimental data.
Introduction to the Brain Imaging Data Structure (BIDS): a standard for organizing human neuroimaging datasets. This lecture was part of the 2018 Neurohackademy, a 2-week hands-on summer institute in neuroimaging and data science held at the University of Washington eScience Institute.
NWB: An ecosystem for neurophysiology data standardization
NWB: An ecosystem for neurophysiology data standardization
DAQCORD is a framework for the design, documentation and reporting of data curation methods in order to advance the scientific rigour, reproducibility and analysis of the data. This lecture covers the rationale for developing the framework, the process in which the framework was developed, and ends with a presentation of the framework. While the driving use case for DAQCORD was clinical traumatic brain injury research, the framework is applicable to clinical studies in other domains of clinical neuroscience research.
PyNN is a simulator-independent language for building neuronal network models. The PyNN API aims to support modelling at a high-level of abstraction (populations of neurons, layers, columns and the connections between them) while still allowing access to the details of individual neurons and synapses when required. PyNN provides a library of standard neuron, synapse, and synaptic plasticity models which have been verified to work the same on the different supported simulators. PyNN also provides a set of commonly-used connectivity algorithms (e.g. all-to-all, random, distance-dependent, small-world) but makes it easy to provide your own connectivity in a simulator-independent way. This lecture was part of the 7th SpiNNaker Workshop held 3 - 6 October 2017.
This lecture and tutorial focuses on measuring human functional brain networks. The lecture and tutorial were part of the 2019 Neurohackademy, a 2-week hands-on summer institute in neuroimaging and data science held at the University of Washington eScience Institute.
Lecture on functional brain parcellations and a set of tutorials on bootstrap agregation of stable clusters (BASC) for fMRI brain parcellation which were part of the 2019 Neurohackademy, a 2-week hands-on summer institute in neuroimaging and data science held at the University of Washington eScience Institute.
Neuronify is an educational tool meant to create intuition for how neurons and neural networks behave. You can use it to combine neurons with different connections, just like the ones we have in our brain, and explore how changes on single cells lead to behavioral changes in important networks. Neuronify is based on an integrate-and-fire model of neurons. This is one of the simplest models of neurons that exist. It focuses on the spike timing of a neuron and ignores the details of the action potential dynamics. These neurons are modeled as simple RC circuits. When the membrane potential is above a certain threshold, a spike is generated and the voltage is reset to its resting potential. This spike then signals other neurons through its synapses.
Neuronify aims to provide a low entry point to simulation-based neuroscience.
This lecture covers an introduction to connectomics, and image processing tools for the study of connectomics.
This lecture covers acquisition techniques, the physics of MRI, diffusion imaging, prediction using fMRI.
Optical imaging offers a look inside the working brain. This lecture takes a look at orientation and ocular dominance columns in the visual cortex, and shows how they can be viewed with calcium imaging.
Functional imaging has led to the discovery of a plethora of visual cortical regions. This lecture introduces functional imaging techniques and their teachings about the visual cortex.