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This lecture covers computational principles that growth cones employ to detect and respond to environmental chemotactic gradients, focusing particularly on growth-cone shape dynamics.

Difficulty level: Intermediate
Duration: 26:12
Speaker: : Geoff Goodhill

In this lecture you will learn that in developing mouse somatosensory cortex, endogenous Btbd3 translocate to the cell nucleus in response to neuronal activity and oriente primary dendrites toward active axons in the barrel hollow.

Difficulty level: Intermediate
Duration: 27:32
Speaker: : Tomomi Shimogori

In this presentation, the speaker describes some of their recent efforts to characterize the transcriptome of the developing human brain, and and introduction to the BrainSpan project.

Difficulty level: Intermediate
Duration: 30:45
Speaker: : Nenad Sestan

How does the brain learn? This lecture discusses the roles of development and adult plasticity in shaping functional connectivity.

Difficulty level: Beginner
Duration: 1:08:45
Speaker: : Clay Reid

This lecture focuses on how the immune system can target and attack the nervous system to produce autoimmune responses that may result in diseases such as multiple sclerosis, neuromyelitis, and lupus cerebritis manifested by motor, sensory, and cognitive impairments. Despite the fact that the brain is an immune-privileged site, autoreactive lymphocytes producing proinflammatory cytokines can cause active brain inflammation, leading to myelin and axonal loss.

Difficulty level: Beginner
Duration: 37:36
Speaker: : Anat Achiron

This lecture provides an introduction to the study of eye-tracking in humans. 

Difficulty level: Beginner
Duration: 34:05
Speaker: : Ulrich Ettinger

From the retina to the superior colliculus, the lateral geniculate nucleus into primary visual cortex and beyond, this lecture gives a tour of the mammalian visual system highlighting the Nobel-prize winning discoveries of Hubel & Wiesel.

Difficulty level: Beginner
Duration: 56:31
Speaker: : Clay Reid

From Universal Turing Machines to McCulloch-Pitts and Hopfield associative memory networks, this lecture explains what is meant by computation.

Difficulty level: Beginner
Duration: 55:27
Speaker: : Christof Koch

In an overview of the structure of the mammalian neocortex, this lecture explains how the mammalian cortex is organized in a hierarchy, describing the columnar principle and canonical microcircuits.

Difficulty level: Beginner
Duration: 1:02:02
Speaker: : Clay Reid

The retina has 60 different types of neurons. What are their functions? This lecture explores the definition of cell types and their functions in the mammalian retina.

Difficulty level: Beginner
Duration: 1:07:19
Speaker: : Christof Koch

Optical imaging offers a look inside the working brain. This lecture takes a look at orientation and ocular dominance columns in the visual cortex, and shows how they can be viewed with calcium imaging.

Difficulty level: Beginner
Duration: 26:17
Speaker: : Clay Reid

Functional imaging has led to the discovery of a plethora of visual cortical regions. This lecture introduces functional imaging techniques and their teachings about the visual cortex.

Difficulty level: Beginner
Duration: 1:07:03
Speaker: : Clay Reid

This lecture explains these ideas and explores the task of characterizing neuronal response properties using information theory.

Difficulty level: Beginner
Duration: 1:01:18
Speaker: : Christof Koch

What is color? This lecture explores how color is "made" in the brain and variations of color perception including trichromacy, color blindness in men, tetrachromatic vision in women, and genetic engineering of color perception.

Difficulty level: Beginner
Duration: 1:11:07
Speaker: : Christof Koch

What is the difference between attention and consciousness? This lecture describes the scientific meaning of consciousness, journeys on the search for neural correlates of visual consciousness, and explores the possibility of consciousness in other beings and even non-biological structures.

Difficulty level: Beginner
Duration: 1:10:01
Speaker: : Christof Koch

This primer on optogenetics primer discusses how to manipulate neuronal populations with light at millisecond resolution and offers possible applications such as curing the blind and "playing the piano" with cortical neurons.

Difficulty level: Beginner
Duration: 59:06
Speaker: : Clay Reid

This lecture explains the concept of federated analysis in the context of medical data, associated challenges. The lecture also presents an example of hospital federations via the Medical Informatics Platform.

Difficulty level: Intermediate
Duration: 19:15
Speaker: : Yannis Ioannidis

This lesson continues with the second workshop on reproducible science, focusing on additional open source tools for researchers and data scientists, such as the R programming language for data science, as well as associated tools like RStudio and R Markdown. Additionally, users are introduced to Python and iPython notebooks, Google Colab, and are given hands-on tutorials on how to create a Binder environment, as well as various containers in Docker and Singularity.

Difficulty level: Beginner
Duration: 1:16:04

This lesson contains both a lecture and a tutorial component. The lecture (0:00-20:03 of YouTube video) discusses both the need for intersectional approaches in healthcare as well as the impact of neglecting intersectionality in patient populations. The lecture is followed by a practical tutorial in both Python and R on how to assess intersectional bias in datasets. Links to relevant code and data are found below. 

Difficulty level: Beginner
Duration: 52:26

This is a hands-on tutorial on PLINK, the open source whole genome association analysis toolset. The aims of this tutorial are to teach users how to perform basic quality control on genetic datasets, as well as to identify and understand GWAS summary statistics. 

Difficulty level: Intermediate
Duration: 1:27:18
Speaker: : Dan Felsky