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The Mouse Phenome Database (MPD) provides access to primary experimental trait data, genotypic variation, protocols and analysis tools for mouse genetic studies. Data are contributed by investigators worldwide and represent a broad scope of phenotyping endpoints and disease-related traits in naïve mice and those exposed to drugs, environmental agents or other treatments. MPD ensures rigorous curation of phenotype data and supporting documentation using relevant ontologies and controlled vocabularies. As a repository of curated and integrated data, MPD provides a means to access/re-use baseline data, as well as allows users to identify sensitized backgrounds for making new mouse models with genome editing technologies, analyze trait co-inheritance, benchmark assays in their own laboratories, and many other research applications. MPD’s primary source of funding is NIDA. For this reason, a majority of MPD data is neuro- and behavior-related.

Difficulty level: Beginner
Duration: 55:36
Speaker: : Elissa Chesler

Overview of the content for Day 1 of this course.

Difficulty level: Beginner
Duration: 00:01:59
Speaker: : Tristan Shuman

Overview of Day 2 of this course.

Difficulty level: Beginner
Duration: 00:03:28
Speaker: : Tristan Shuman

Best practices: the tips and tricks on how to get your Miniscope to work and how to get your experiments off the ground.

Difficulty level: Beginner
Duration: 00:53:34

This talk compares various sensors and resolutions for in vivo neural recordings.

Difficulty level: Beginner
Duration: 00:24:03

This talk delves into challenges and opportunities of Miniscope design, seeking the optimal balance between scale and function.

Difficulty level: Beginner
Duration: 00:21:51

Attendees of this talk will learn aobut computational imaging systems and associated pipelines, as well as open-source software solutions supporting miniscope use.

Difficulty level: Beginner
Duration: 00:17:56

This lecture introduces neuroscience concepts and methods such as fMRI, visual respones in BOLD data, and the eccentricity of visual receptive fields. 

Difficulty level: Intermediate
Duration: 7:15
Speaker: : Mike X. Cohen

This tutorial walks users through the creation and visualization of activation flat maps from fMRI datasets. 

Difficulty level: Intermediate
Duration: 12:15
Speaker: : Mike X. Cohen

This talk covers the present state and future directions of calcium imaging data analysis, particularly in the context of one-photon vs two-photon approaches. 

Difficulty level: Beginner
Duration: 00:21:06

This tutorial demonstrates to users the conventional preprocessing steps when working with BOLD signal datasets from fMRI. 

Difficulty level: Intermediate
Duration: 12:05
Speaker: : Mike X. Cohen

In this tutorial, users will learn how to create a trial-averaged BOLD response and store it in a matrix in MATLAB. 

Difficulty level: Intermediate
Duration: 20:12
Speaker: : Mike X. Cohen

This tutorial teaches users how to create animations of BOLD responses over time, to allow researchers and clinicians to visualize time-course activity patterns.

Difficulty level: Intermediate
Duration: 12:52
Speaker: : Mike X. Cohen

This tutorial demonstrates how to use MATLAB to create event-related BOLD time courses from fMRI datasets. 

Difficulty level: Intermediate
Duration: 13:39
Speaker: : Mike X. Cohen

In this tutorial, users learn how to compute and visualize a t-test on experimental condition differences.

Difficulty level: Intermediate
Duration: 17:54
Speaker: : Mike X. Cohen

In this talk, results from rodent experimentation using in vivo imaging are presented, demonstrating how the monitoring of neural ensembles may reveal patterns of learning during spatial tasks.

Difficulty level: Beginner
Duration: 00:19:43

How to start processing the raw imaging data generated with a Miniscope, including developing a usable pipeline and demoing the Minion pipeline.

Difficulty level: Beginner
Duration: 00:57:26

The direction of miniature microscopes, including both MetaCell and other groups.

Difficulty level: Beginner
Duration: 00:49:16

Overview of the content for Day 2 of this course.

Difficulty level: Beginner
Duration: 00:11:01
Speaker: : Tristan Shuman

Summary and closing remarks for this three-day course.

Difficulty level: Beginner
Duration: 00:04:56
Speaker: : Stephen Larson