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This lesson is a general overview of overarching concepts in neuroinformatics research, with a particular focus on clinical approaches to defining, measuring, studying, diagnosing, and treating various brain disorders. Also described are the complex, multi-level nature of brain disorders and the data associated with them, from genes and individual cells up to cortical microcircuits and whole-brain network dynamics. Given the heterogeneity of brain disorders and their underlying mechanisms, this lesson lays out a case for multiscale neuroscience data integration.

Difficulty level: Intermediate
Duration: 1:09:33
Speaker: : Sean Hill

This is the first of two workshops on reproducibility in science, during which participants are introduced to concepts of FAIR and open science. After discussing the definition of and need for FAIR science, participants are walked through tutorials on installing and using Github and Docker, the powerful, open-source tools for versioning and publishing code and software, respectively.

Difficulty level: Intermediate
Duration: 1:20:58

This is a hands-on tutorial on PLINK, the open source whole genome association analysis toolset. The aims of this tutorial are to teach users how to perform basic quality control on genetic datasets, as well as to identify and understand GWAS summary statistics. 

Difficulty level: Intermediate
Duration: 1:27:18
Speaker: : Dan Felsky

This is a tutorial on using the open-source software PRSice to calculate a set of polygenic risk scores (PRS) for a study sample. Users will also learn how to read PRS into R, visualize distributions, and perform basic association analyses. 

Difficulty level: Intermediate
Duration: 1:53:34
Speaker: : Dan Felsky

This lesson is an overview of transcriptomics, from fundamental concepts of the central dogma and RNA sequencing at the single-cell level, to how genetic expression underlies diversity in cell phenotypes. 

Difficulty level: Intermediate
Duration: 1:29:08

This is a continuation of the talk on the cellular mechanisms of neuronal communication, this time at the level of brain microcircuits and associated global signals like those measureable by electroencephalography (EEG). This lecture also discusses EEG biomarkers in mental health disorders, and how those cortical signatures may be simulated digitally.

Difficulty level: Intermediate
Duration: 1:11:04
Speaker: : Etay Hay

In this third and final hands-on tutorial from the Research Workflows for Collaborative Neuroscience workshop, you will learn about workflow orchestration using open source tools like DataJoint and Flyte. 

Difficulty level: Intermediate
Duration: 22:36
Speaker: : Daniel Xenes

This lecture aims to help researchers, students, and health care professionals understand the place for neuroinformatics in the patient journey using the exemplar of an epilepsy patient. 

Difficulty level: Intermediate
Duration: 1:32:53

This lecture describes how to build research workflows, including a demonstrate using DataJoint Elements to build data pipelines.

Difficulty level: Intermediate
Duration: 47:00
Speaker: : Dimitri Yatsenko

This video will document the process of creating a pipeline rule for batch processing on brainlife.

Difficulty level: Intermediate
Duration: 0:57
Speaker: :

While the previous lesson in the Neuro4ML course dealt with the mechanisms involved in individual synapses, this lesson discusses how synapses and their neurons' firing patterns may change over time. 

Difficulty level: Intermediate
Duration: 4:48
Speaker: : Marcus Ghosh

In this lesson, you will learn about how machine learners and computational neuroscientists design and build models of neuronal synapses. 

Difficulty level: Intermediate
Duration: 8:59
Speaker: : Dan Goodman

This lesson characterizes different types of learning in a neuroscientific and cellular context, and various models employed by researchers to investigate the mechanisms involved. 

Difficulty level: Intermediate
Duration: 3:54
Speaker: : Dan Goodman

In this lesson, you will learn about different approaches to modeling learning in neural networks, particularly focusing on system parameters such as firing rates and synaptic weights impact a network. 

Difficulty level: Intermediate
Duration: 9:40
Speaker: : Dan Goodman

This video gives a brief introduction to Neuro4ML's lessons on neuromorphic computing - the use of specialized hardware which either directly mimics brain function or is inspired by some aspect of the way the brain computes. 

Difficulty level: Intermediate
Duration: 3:56
Speaker: : Dan Goodman

In this lesson, you will learn in more detail about neuromorphic computing, that is, non-standard computational architectures that mimic some aspect of the way the brain works. 

Difficulty level: Intermediate
Duration: 10:08
Speaker: : Dan Goodman

This video provides a very quick introduction to some of the neuromorphic sensing devices, and how they offer unique, low-power applications.

Difficulty level: Intermediate
Duration: 2:37
Speaker: : Dan Goodman

In this lecture, the speaker demonstrates Neurokernel's module interfacing feature by using it to integrate independently developed models of olfactory and vision LPUs based upon experimentally obtained connectivity information.

Difficulty level: Intermediate
Duration: 29:56
Speaker: : Aurel A. Lazar

This lesson presents a simulation software for spatial model neurons and their networks designed primarily for GPUs.

Difficulty level: Intermediate
Duration: 21:15
Speaker: : Tadashi Yamazaki

The lecture covers a brief introduction to neuromorphic engineering, some of the neuromorphic networks that the speaker has developed, and their potential applications, particularly in machine learning.

Difficulty level: Intermediate
Duration: 19:57