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This lesson is a general overview of overarching concepts in neuroinformatics research, with a particular focus on clinical approaches to defining, measuring, studying, diagnosing, and treating various brain disorders. Also described are the complex, multi-level nature of brain disorders and the data associated with them, from genes and individual cells up to cortical microcircuits and whole-brain network dynamics. Given the heterogeneity of brain disorders and their underlying mechanisms, this lesson lays out a case for multiscale neuroscience data integration.

Difficulty level: Intermediate
Duration: 1:09:33
Speaker: : Sean Hill

This is a hands-on tutorial on PLINK, the open source whole genome association analysis toolset. The aims of this tutorial are to teach users how to perform basic quality control on genetic datasets, as well as to identify and understand GWAS summary statistics. 

Difficulty level: Intermediate
Duration: 1:27:18
Speaker: : Dan Felsky

This is a tutorial on using the open-source software PRSice to calculate a set of polygenic risk scores (PRS) for a study sample. Users will also learn how to read PRS into R, visualize distributions, and perform basic association analyses. 

Difficulty level: Intermediate
Duration: 1:53:34
Speaker: : Dan Felsky

This is an introductory lecture on whole-brain modelling, delving into the various spatial scales of neuroscience, neural population models, and whole-brain modelling. Additionally, the clinical applications of building and testing such models are characterized. 

Difficulty level: Intermediate
Duration: 1:24:44
Speaker: : John Griffiths

This lesson breaks down the principles of Bayesian inference and how it relates to cognitive processes and functions like learning and perception. It is then explained how cognitive models can be built using Bayesian statistics in order to investigate how our brains interface with their environment. 

This lesson corresponds to slides 1-64 in the PDF below. 

Difficulty level: Intermediate
Duration: 1:28:14

This lesson describes spike timing-dependent plasticity (STDP), a biological process that adjusts the strength of connections between neurons in the brain, and how one can implement or mimic this process in a computational model. You will also find links for practical exercises at the bottom of this page. 

Difficulty level: Intermediate
Duration: 12:50
Speaker: : Dan Goodman

This lesson discusses a gripping neuroscientific question: why have neurons developed the discrete action potential, or spike, as a principle method of communication? 

Difficulty level: Intermediate
Duration: 9:34
Speaker: : Dan Goodman

This tutorial covers the fundamentals of collaborating with Git and GitHub.

Difficulty level: Intermediate
Duration: 2:15:50
Speaker: : Elizabeth DuPre

This lecture and tutorial focuses on measuring human functional brain networks, as well as how to account for inherent variability within those networks. 

Difficulty level: Intermediate
Duration: 50:44
Speaker: : Caterina Gratton

This lesson provides an overview of Jupyter notebooks, Jupyter lab, and Binder, as well as their applications within the field of neuroimaging, particularly when it comes to the writing phase of your research. 

Difficulty level: Intermediate
Duration: 50:28
Speaker: : Elizabeth DuPre

Learn how to create a standard extracellular electrophysiology dataset in NWB using Python.

Difficulty level: Intermediate
Duration: 23:10
Speaker: : Ryan Ly

Learn how to create a standard calcium imaging dataset in NWB using Python.

Difficulty level: Intermediate
Duration: 31:04
Speaker: : Ryan Ly

In this tutorial, you will learn how to create a standard intracellular electrophysiology dataset in NWB using Python.

Difficulty level: Intermediate
Duration: 20:23
Speaker: : Pamela Baker

In this tutorial, you will learn how to use the icephys-metadata extension to enter meta-data detailing your experimental paradigm.

Difficulty level: Intermediate
Duration: 27:18
Speaker: : Oliver Ruebel

In this tutorial, users learn how to create a standard extracellular electrophysiology dataset in NWB using MATLAB.

Difficulty level: Intermediate
Duration: 45:46
Speaker: : Ben Dichter

Learn how to create a standard calcium imaging dataset in NWB using MATLAB.

Difficulty level: Intermediate
Duration: 39:10
Speaker: : Ben Dichter

Learn how to create a standard intracellular electrophysiology dataset in NWB.

Difficulty level: Intermediate
Duration: 20:22
Speaker: : Pamela Baker

This lesson gives an overview of the Brainstorm package for analyzing extracellular electrophysiology, including preprocessing, spike sorting, trial alignment, and spectrotemporal decomposition.

Difficulty level: Intermediate
Duration: 47:47

This lesson provides an overview of the CaImAn package, as well as a demonstration of usage with NWB.

Difficulty level: Intermediate
Duration: 44:37

This lesson gives an overview of the SpikeInterface package, including demonstration of data loading, preprocessing, spike sorting, and comparison of spike sorters.

Difficulty level: Intermediate
Duration: 1:10:28
Speaker: : Alessio Buccino