This lesson is a general overview of overarching concepts in neuroinformatics research, with a particular focus on clinical approaches to defining, measuring, studying, diagnosing, and treating various brain disorders. Also described are the complex, multi-level nature of brain disorders and the data associated with them, from genes and individual cells up to cortical microcircuits and whole-brain network dynamics. Given the heterogeneity of brain disorders and their underlying mechanisms, this lesson lays out a case for multiscale neuroscience data integration.

This is a hands-on tutorial on PLINK, the open source whole genome association analysis toolset. The aims of this tutorial are to teach users how to perform basic quality control on genetic datasets, as well as to identify and understand GWAS summary statistics. 

This is a tutorial on using the open-source software PRSice to calculate a set of polygenic risk scores (PRS) for a study sample. Users will also learn how to read PRS into R, visualize distributions, and perform basic association analyses. 

This is a continuation of the talk on the cellular mechanisms of neuronal communication, this time at the level of brain microcircuits and associated global signals like those measureable by electroencephalography (EEG). This lecture also discusses EEG biomarkers in mental health disorders, and how those cortical signatures may be simulated digitally.

This is an introductory lecture on whole-brain modelling, delving into the various spatial scales of neuroscience, neural population models, and whole-brain modelling. Additionally, the clinical applications of building and testing such models are characterized. 

This lecture aims to help researchers, students, and health care professionals understand the place for neuroinformatics in the patient journey using the exemplar of an epilepsy patient. 

This lesson introduces the practical exercises which accompany the previous lessons on animal and human connectomes in the brain and nervous system. 

This lesson describes spike timing-dependent plasticity (STDP), a biological process that adjusts the strength of connections between neurons in the brain, and how one can implement or mimic this process in a computational model. You will also find links for practical exercises at the bottom of this page. 

This lesson discusses a gripping neuroscientific question: why have neurons developed the discrete action potential, or spike, as a principle method of communication? 

This lecture provides an introduction to the Brain Imaging Data Structure (BIDS), a standard for organizing human neuroimaging datasets.

This lesson provides an overview of Jupyter notebooks, Jupyter lab, and Binder, as well as their applications within the field of neuroimaging, particularly when it comes to the writing phase of your research. 

Learn how to create a standard extracellular electrophysiology dataset in NWB using Python.

Learn how to create a standard calcium imaging dataset in NWB using Python.

In this tutorial, you will learn how to create a standard intracellular electrophysiology dataset in NWB using Python.

In this tutorial, you will learn how to use the icephys-metadata extension to enter meta-data detailing your experimental paradigm.

In this tutorial, users learn how to create a standard extracellular electrophysiology dataset in NWB using MATLAB.

Learn how to create a standard calcium imaging dataset in NWB using MATLAB.

Learn how to create a standard intracellular electrophysiology dataset in NWB.

This lesson gives an overview of the Brainstorm package for analyzing extracellular electrophysiology, including preprocessing, spike sorting, trial alignment, and spectrotemporal decomposition.

This lesson provides an overview of the CaImAn package, as well as a demonstration of usage with NWB.