This lesson is a general overview of overarching concepts in neuroinformatics research, with a particular focus on clinical approaches to defining, measuring, studying, diagnosing, and treating various brain disorders. Also described are the complex, multi-level nature of brain disorders and the data associated with them, from genes and individual cells up to cortical microcircuits and whole-brain network dynamics. Given the heterogeneity of brain disorders and their underlying mechanisms, this lesson lays out a case for multiscale neuroscience data integration.
This lesson describes the fundamentals of genomics, from central dogma to design and implementation of GWAS, to the computation, analysis, and interpretation of polygenic risk scores.
This lesson contains the slides (pptx) of a lecture discussing the necessary concepts and tools for taking into account population stratification and admixture in the context of genome-wide association studies (GWAS). The free-access software Tractor and its advantages in GWAS are also discussed.
This lesson is an overview of transcriptomics, from fundamental concepts of the central dogma and RNA sequencing at the single-cell level, to how genetic expression underlies diversity in cell phenotypes.
This lesson describes the principles underlying functional magnetic resonance imaging (fMRI), diffusion-weighted imaging (DWI), tractography, and parcellation. These tools and concepts are explained in a broader context of neural connectivity and mental health.
This is an introductory lecture on whole-brain modelling, delving into the various spatial scales of neuroscience, neural population models, and whole-brain modelling. Additionally, the clinical applications of building and testing such models are characterized.
This lesson breaks down the principles of Bayesian inference and how it relates to cognitive processes and functions like learning and perception. It is then explained how cognitive models can be built using Bayesian statistics in order to investigate how our brains interface with their environment.
This lesson corresponds to slides 1-64 in the PDF below.
This lecture provides an introduction to the Brain Imaging Data Structure (BIDS), a standard for organizing human neuroimaging datasets.
This tutorial covers the fundamentals of collaborating with Git and GitHub.
This lecture and tutorial focuses on measuring human functional brain networks, as well as how to account for inherent variability within those networks.
This lecture introduces you to the basics of the Amazon Web Services public cloud. It covers the fundamentals of cloud computing and goes through both the motivations and processes involved in moving your research computing to the cloud.
This lecture gives an overview of how to prepare and preprocess neuroimaging (EEG/MEG) data for use in TVB.
This lecture focuses on ontologies for clinical neurosciences.
This talk presents state-of-the-art methods for ensuring data privacy with a particular focus on medical data sharing across multiple organizations.
This lecture talks about the usage of knowledge graphs in hospitals and related challenges of semantic interoperability.