Explore how to setup an epileptic seizure simulation with the TVB graphical user interface. This lesson will show you how to program the epileptor model in the brain network to simulate a epileptic seizure originating in the hippocampus. It will also show how to upload and view mouse connectivity data, as well as give a short introduction to the python script interface of TVB.
This lesson is a general overview of overarching concepts in neuroinformatics research, with a particular focus on clinical approaches to defining, measuring, studying, diagnosing, and treating various brain disorders. Also described are the complex, multi-level nature of brain disorders and the data associated with them, from genes and individual cells up to cortical microcircuits and whole-brain network dynamics. Given the heterogeneity of brain disorders and their underlying mechanisms, this lesson lays out a case for multiscale neuroscience data integration.
In this tutorial on simulating whole-brain activity using Python, participants can follow along using corresponding code and repositories, learning the basics of neural oscillatory dynamics, evoked responses and EEG signals, ultimately leading to the design of a network model of whole-brain anatomical connectivity.
This lesson breaks down the principles of Bayesian inference and how it relates to cognitive processes and functions like learning and perception. It is then explained how cognitive models can be built using Bayesian statistics in order to investigate how our brains interface with their environment.
This lesson corresponds to slides 1-64 in the PDF below.
This lecture and tutorial focuses on measuring human functional brain networks. The lecture and tutorial were part of the 2019 Neurohackademy, a 2-week hands-on summer institute in neuroimaging and data science held at the University of Washington eScience Institute.
Introduction to the central concepts of machine learning, and how they can be applied in Python using the Scikit-learn Package. This lecture was part of the 2018 Neurohackademy, a 2-week hands-on summer institute in neuroimaging and data science held at the University of Washington eScience Institute.
This is a continuation of the talk on the cellular mechanisms of neuronal communication, this time at the level of brain microcircuits and associated global signals like those measureable by electroencephalography (EEG). This lecture also discusses EEG biomarkers in mental health disorders, and how those cortical signatures may be simulated digitally.
This lecture on multi-scale entropy by Jil Meier is part of the TVB Node 10 series, a 4 day workshop dedicated to learning about The Virtual Brain, brain imaging, brain simulation, personalised brain models, TVB use cases, etc. TVB is a full brain simulation platform.
DAQCORD is a framework for the design, documentation and reporting of data curation methods in order to advance the scientific rigour, reproducibility and analysis of the data. This lecture covers the rationale for developing the framework, the process in which the framework was developed, and ends with a presentation of the framework. While the driving use case for DAQCORD was clinical traumatic brain injury research, the framework is applicable to clinical studies in other domains of clinical neuroscience research.
This tutorial demonstrates how to perform cell-type deconvolution in order to estimate how proportions of cell-types in the brain change in response to various conditions. While these techniques may be useful in addressing a wide range of scientific questions, this tutorial will focus on the cellular changes associated with major depression (MDD).
This lesson explains the fundamental principles of neuronal communication, such as neuronal spiking, membrane potentials, and cellular excitability, and how these electrophysiological features of the brain may be modelled and simulated digitally.
This is an in-depth guide on EEG signals and their interaction within brain microcircuits. Participants are also shown techniques and software for simulating, analyzing, and visualizing these signals.
This lesson describes the principles underlying functional magnetic resonance imaging (fMRI), diffusion-weighted imaging (DWI), tractography, and parcellation. These tools and concepts are explained in a broader context of neural connectivity and mental health.