Explore how to setup an epileptic seizure simulation with the TVB graphical user interface. This lesson will show you how to program the epileptor model in the brain network to simulate a epileptic seizure originating in the hippocampus. It will also show how to upload and view mouse connectivity data, as well as give a short introduction to the python script interface of TVB.
This lesson is a general overview of overarching concepts in neuroinformatics research, with a particular focus on clinical approaches to defining, measuring, studying, diagnosing, and treating various brain disorders. Also described are the complex, multi-level nature of brain disorders and the data associated with them, from genes and individual cells up to cortical microcircuits and whole-brain network dynamics. Given the heterogeneity of brain disorders and their underlying mechanisms, this lesson lays out a case for multiscale neuroscience data integration.
In this tutorial on simulating whole-brain activity using Python, participants can follow along using corresponding code and repositories, learning the basics of neural oscillatory dynamics, evoked responses and EEG signals, ultimately leading to the design of a network model of whole-brain anatomical connectivity.
This lesson breaks down the principles of Bayesian inference and how it relates to cognitive processes and functions like learning and perception. It is then explained how cognitive models can be built using Bayesian statistics in order to investigate how our brains interface with their environment.
This lesson corresponds to slides 1-64 in the PDF below.
Whereas the previous two lessons described the biophysical and signalling properties of individual neurons, this lesson describes properties of those units when part of larger networks.
This lesson goes over some examples of how machine learners and computational neuroscientists go about designing and building neural network models inspired by biological brain systems.
This lecture and tutorial focuses on measuring human functional brain networks, as well as how to account for inherent variability within those networks.
This video will document the process of creating a pipeline rule for batch processing on brainlife.
This video will document the process of launching a Jupyter Notebook for group-level analyses directly from brainlife.
This lecture introduces you to the basics of the Amazon Web Services public cloud. It covers the fundamentals of cloud computing and goes through both the motivations and processes involved in moving your research computing to the cloud.
This lecture introduces neuroscience concepts and methods such as fMRI, visual respones in BOLD data, and the eccentricity of visual receptive fields.
In this tutorial, users learn how to compute and visualize a t-test on experimental condition differences.
This is a hands-on tutorial on PLINK, the open source whole genome association analysis toolset. The aims of this tutorial are to teach users how to perform basic quality control on genetic datasets, as well as to identify and understand GWAS summary statistics.
As the previous lesson of this course described how researchers acquire neural data, this lesson will discuss how to go about interpreting and analysing the data.
In this lesson, you will learn about one particular aspect of decision making: reaction times. In other words, how long does it take to take a decision based on a stream of information arriving continuously over time?
This lesson goes over the basic mechanisms of neural synapses, the space between neurons where signals may be transmitted.
This lesson describes spike timing-dependent plasticity (STDP), a biological process that adjusts the strength of connections between neurons in the brain, and how one can implement or mimic this process in a computational model. You will also find links for practical exercises at the bottom of this page.
This lesson discusses a gripping neuroscientific question: why have neurons developed the discrete action potential, or spike, as a principle method of communication?
This tutorial demonstrates how to perform cell-type deconvolution in order to estimate how proportions of cell-types in the brain change in response to various conditions. While these techniques may be useful in addressing a wide range of scientific questions, this tutorial will focus on the cellular changes associated with major depression (MDD).
This lesson explains the fundamental principles of neuronal communication, such as neuronal spiking, membrane potentials, and cellular excitability, and how these electrophysiological features of the brain may be modelled and simulated digitally.