In this lecture you will learn that in developing mouse somatosensory cortex, endogenous Btbd3 translocate to the cell nucleus in response to neuronal activity and oriente primary dendrites toward active axons in the barrel hollow.
In this presentation, the speaker describes some of their recent efforts to characterize the transcriptome of the developing human brain, and and introduction to the BrainSpan project.
Following the previous lesson on neuronal structure, this lesson discusses neuronal function, particularly focusing on spike triggering and propogation.
This lesson introduces the practical exercises which accompany the previous lessons on animal and human connectomes in the brain and nervous system.
This lesson discusses a gripping neuroscientific question: why have neurons developed the discrete action potential, or spike, as a principle method of communication?
This lecture covers NeuronUnit, a library that builds upon SciUnit and integrates with several existing neuroinformatics resources to support validating single-neuron models using data gathered by neurophysiologists.
This lesson provides an introduction to the NeuroElectro project, which aims to organize information on cellular neurophysiology.
This lesson covers simultaneously recorded neurons in non-human primates coordinate their spiking activity in a sequential manner that mirrors the dominant wave propagation directions of the local field potentials.
This talk covers statistical analysis of spike train data, the modeling approach GLM, and the problem of assessing neural synchrony.
This talk covers statistical methods for characterizing neural population responses and extracting structure from high-dimensional neural data.
This presentation discusses research aimed at understanding the activity of single neurons and populations of neurons in the visual system.
This lecture explains the concept of federated analysis in the context of medical data, associated challenges. The lecture also presents an example of hospital federations via the Medical Informatics Platform.
This is a hands-on tutorial on PLINK, the open source whole genome association analysis toolset. The aims of this tutorial are to teach users how to perform basic quality control on genetic datasets, as well as to identify and understand GWAS summary statistics.
This is a tutorial on using the open-source software PRSice to calculate a set of polygenic risk scores (PRS) for a study sample. Users will also learn how to read PRS into R, visualize distributions, and perform basic association analyses.
This lesson is an overview of transcriptomics, from fundamental concepts of the central dogma and RNA sequencing at the single-cell level, to how genetic expression underlies diversity in cell phenotypes.
This is a tutorial introducing participants to the basics of RNA-sequencing data and how to analyze its features using Seurat.
This tutorial demonstrates how to perform cell-type deconvolution in order to estimate how proportions of cell-types in the brain change in response to various conditions. While these techniques may be useful in addressing a wide range of scientific questions, this tutorial will focus on the cellular changes associated with major depression (MDD).
This is a tutorial on how to simulate neuronal spiking in brain microcircuit models, as well as how to analyze, plot, and visualize the corresponding data.
This lightning talk describes an automated pipline for positron emission tomography (PET) data.
In this third and final hands-on tutorial from the Research Workflows for Collaborative Neuroscience workshop, you will learn about workflow orchestration using open source tools like DataJoint and Flyte.